REVIEW
Clotrimazole as the Standard Treatment for Otomycosis: An Analysis of Effectiveness Compared to Selected Antifungal Treatment Methods in Fungal External Otitis. State-of-the-Art Review
Adrianna Domańska , Aleksandra Łubińska-Kowalska, Adrianna Witkowska, Julia Piotrowska, Antonina Teresa Witkowska, Barbara Anna Zapalska, Krzysztof Julian Długosz, Agata Żak-Gontarz, Aleksandra Minda, Justyna Janikowska, Monika Wendland
Otomycosis or fungal external otitis is a fungal infection of the external auditory canal, typically caused by Aspergillus and Candida species. This review aims to summarize current research on the effectiveness of clotrimazole in treating otomycosis, comparing it with other antifungal treatments
Medical Science, 2025, 29, e77ms3578
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Effects of contraceptive choice on vaginal microbiome: current evidence and perspectives
Justyna Kuciel, Dominik Tomczak, Maria Mroczka, Kinga Erazmus, Roksana Hrapkowicz, Agnieszka Czernecka, Kinga Świtała, Patrycja Pysz, Marek Borecki, Karolina Jałocha
Lactobacillus species are the most significant bacteria present in the vaginal microbiome, as they protect the female reproductive system against infections by, for example, releasing protective substances and regulating vaginal pH.
Medical Science, 2025, 29, e78ms3577
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Shin Splints - a hidden epidemic among runners and athletes: a review of the current state of knowledge
Przemysław Ciszewski, Alicja Drelichowska, Michał Azierski
Shin splints, also known as medial tibial stress syndrome (MTSS), are a common occurrence for runners and other athletes. It is characterized by pain along the inner edge of the shinbone, usually brought on by an excessive amount of strain on the muscles and bone
Medical Science, 2025, 29, e79ms3571
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Irisin – A Multifunctional Myokine with Therapeutic Potential in Metabolic, Cardiovascular, Neurodegenerative, and Musculoskeletal Diseases
Dominika Kuc, Katarzyna Cierpiszewska, Aleksandra Garczyk, Jakub Klamecki, Dagmara Skowrońska
The problem of metabolic, cardiovascular, neurodegenerative, and musculoskeletal diseases is incredibly significant these days due to their high occurrence rate among people globally. Irisin is one of the myokines that has become relevant for multiple physiological roles and has therapeutic potential in different diseases.
Medical Science, 2025, 29, e80ms3564
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Accuracy of diagnosing traumatic hemothorax and pneumothorax in the emergency department using chest ultrasound: Systematic review
Mazi Mohammed Alanazi, Mujtaba Matar Alnakhli, Abdullah Fuad Al Mula
Background: A hemothorax in trauma patients must be diagnosed as soon as feasible because chest drainage can save a patient's life. The purpose of this systematic review was to evaluate the accuracy of chest US for the emergency diagnosis of Pneumothorax and Hemothorax in adult trauma patients
Medical Science, 2025, 29, e81ms3589
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Inositol supplementation in the management of Polycystic Ovary Syndrome
Barbara Anna Zapalska, Antonina Teresa Witkowska, Agata Żak-Gontarz, Aleksandra Minda, Justyna Janikowska, Julia Piotrowska, Aleksandra Łubińska- Kowalska, Adrianna Domańska, Adrianna Witkowska, Monika Wendland, Krzysztof Julian Długosz
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder associated with a broad spectrum of symptoms. The exact etiopathogenesis remains unclear. As a result, the therapeutic approach primarily focuses on alleviating symptoms. Inositol is a substance that plays a role in hormonal signal transduction
Medical Science, 2025, 29, e82ms3608
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Effectiveness of Closed Reduction Techniques for Anterior Shoulder Dislocation in the Emergency Department: Systematic review
Mazi Mohammed Alanazi, Nada Abdulmohsen Shaman Almutairi, Fawaz Hindi Alotaibi
Background: The most frequent major joint dislocations seen in emergency rooms are anterior shoulder dislocations. The dislocation is often caused by falls at home or sports accidents.
Medical Science, 2025, 29, e83ms3590
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Effectiveness of observation vs interventional methods in treating adult patients with pneumothorax in emergency department: Systematic review
Mazi Mohammed Alanazi, Abdullah Khalid Alqasim, Abdulelah Hasan Alkhudairi
Background: Pneumothorax (PTX) is a life-threatening illness caused by the air accumulation in the pleural space. It presents as primary, secondary, or traumatic, and its treatment differ depending on size, symptoms, and patient stability.
Medical Science, 2025, 29, e84ms3591
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Histamine Intolerance on Diagnosis and Treatment
Marek Borecki, Karolina Jałocha, Patrycja Pysz, Kinga Świtała, Roksana Hrapkowicz, Agnieszka Czernecka, Kinga Erazmus, Maria Mroczka, Justyna Kuciel, Dominik Tomczak
Histamine intolerance is the imbalance between histamine excess and epithelial breakdown, mainly occurring from impaired digestion of dietary histamine, resulting from a functional deficiency of diamine oxidase (DAO).
Medical Science, 2025, 29, e85ms3580
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Epinephrine use in the emergency department for anaphylaxis management: Systematic review
Mazi Mohammed Alanazi, Raghad Naif Alshareef, Bakheet Atiah Alghamdi
Our study's goal was to evaluate the usage of epinephrine in ED patients who experienced anaphylaxis. Evaluate the route of administration (intravenous, intramuscular, subcutaneous); determine whether epinephrine was used as an initial treatment to manage anaphylaxis
Medical Science, 2025, 29, e86ms3592
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Traumatic brain injury associated intracranial hemorrhage in the emergency department: Systematic review
Mazi Mohammed Alanazi, Wejdan Rubayyi S Alsaiari, Naser AlRashdan
Background: A frequent reason for emergency department (ED) visits is mild traumatic brain injury (mTBI). A traumatic intracranial hemorrhage (ICH) will occur in a small percentage of these individuals, and even fewer may experience serious consequences
