Volume 29, Issue 160, June 2025

A review of contemporary therapeutic strategies for the management of bladder cancer

Justyna Gręda¹, Bartosz Zieliński¹, Karol Mateusz Wojnarowski¹, Anna Klasa², Filip Maj³

¹St. Alexander Hospital in Kielce, Poland
²The University Hospital in Krakow, Poland
³Collegium Medicum, Jan Kochanowski University, Kielce, Poland

ABSTRACT

Introduction: Bladder cancer has become a noteworthy worldwide wellbeing issue, being one of the most frequently analyzed cancers around the world and appearing high rates of recurrence and metastasis. Traditional management strategies, including transurethral resection, intravesical Bacillus Calmette-Guérin (BCG) immunotherapy, and radical cystectomy, have long formed the cornerstone of treatment. Results: Recent developments have significantly changed the treatment landscape for bladder cancer. Recent advances have transformed the therapeutic landscape of bladder cancer. Moreover, inventive sedative conveyance frameworks and consecutive intravesical chemotherapy regimens have tended to neglect the needs in local treatment. In spite of advances, obstacles continue, including treatment resistance, distinguishing reliable biomarkers, long-term security issues, and reasonable access to novel treatments. Conclusions: Recently, how we treat bladder cancer has changed significantly. Our treatment plans now use immunotherapy, targeted therapy, and advanced distribution methods. Proceeding with the investigation is urgent to move forward with quiet determination methods and guarantee impartial access to modern medicines.

Keywords: bladder cancer; immunotherapy; gene therapy; targeted therapy

Medical Science, 2025, 29, e89ms3579

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DOI: https://doi.org/10.54905/disssi.v29i160.e89ms3579

Published: 25 June 2025