Volume 29, Issue 157, March 2025

About the Cover

Background: The most economical method of treating knee osteoarthritis is still total knee replacement. However, a lengthy recovery is frequently linked to the surgery. The purpose of this study was to ascertain how early postoperative pain management and subjective outcomes following total knee replacement were affected by a preoperative radiofrequency ablation intervention. Method: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline was followed in the conduct of this investigation. Two independent reviewers looked for relevant studies published between January 2019 to August 2024 in electronic databases (PubMed, Google Scholar, and Cochrane Library). Results: Six publications from January 2019 to August 2024 are included in this evaluation; the total number of patients included in the trials is 265,713. Three of the included studies found that genicular nerve RFA had no therapeutic effect on postoperative opioid consumption, pain, or functional evaluations at any time when compared to control group; one study found some improvement; and two studies found that traditional RFA combined with fluoroscopy produced positive outcomes for both pain and knee function for those who experienced persistent pain following TKR.

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REVIEW

Efficacy of Radiofrequency ablation of Genicular nerves prior to total knee replacement on postoperative pain: Systematic review

Abdurahman Talal Bahha, Nimah Jameel Dhafar, Sarah Abdulfattah Alsufi, Abdulghani Salah Sadaqa, Abdullah Kamel Alhashmi Alamer, Abed Nabeel Alansari, Ward Hisham Skaik

Background: The most economical method of treating knee osteoarthritis is still total knee replacement. However, a lengthy recovery is frequently linked to the surgery. The purpose of this study was to ascertain how early postoperative pain management and subjective outcomes following total knee replacement

Medical Science, 2025, 29, e43ms3534

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REPORT

Assessment of patients' knowledge level on the prevention of orthopedic injuries: A survey study among physically active individuals

Karolina Jabłońska, Martyna Orzechowska, Michał Orczyk, Aleksandra Roztoczyńska, Aleksandra Jeńć- Magoń, Piotr Paluch, Karol Leśniewski, Jakub Pudźwa, Kamil Gibczyński, Anita Król

The study aimed to evaluate young individuals’ knowledge of orthopedic injuries. It also included evaluating their physical activity level, injury prevention, and understanding of first aid rules

Medical Science, 2025, 29, e44ms3524

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REVIEW

The difference between general anesthesia and peripheral nerve block in terms of postoperative functional recovery after orthopaedic upper limb surgery: Systematic review

Abdurahman Talal Bahha, Bashir Abdulmalik Amin, Suhail Salman Alfaifi, Hammad Sned Alharbi, Abdullah Kamel Alhashmi Alamer, Mohammed Abdulaziz Alduayj, Maram Abdulaziz Aldeej, Shifaa Sharaf Aljefri

Background: Following upper limb procedures, a significant percentage of patients report moderate to severe postoperative pain, and they also tend to consume more opioids over 24 hours following the procedure.

Medical Science, 2025, 29, e45ms3535

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REPORT

Awareness of the population about vitamin D function, deficiency, and its impact on health, supported by survey results

Aleksandra Jeńć-Magoń, Aleksandra Roztoczyńska, Martyna Orzechowska, Karolina Jabłońska, Piotr Paluch, Karol Leśniewski, Jakub Pudźwa, Kamil Gibczyński, Anita Król, Michał Orczyk

Background: Vitamin D plays an important role in the human body, and its deficiency may result in serious consequences such as rickets, osteoporosis, and cause an increased risk of autoimmune diseases, or cancer

Medical Science, 2025, 29, e46ms3511

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Analysis of awareness of the effects of electronic cigarettes on fertility

Aleksandra Roztoczyńska, Aleksandra Jeńć-Magoń, Martyna Orzechowska, Karolina Jablonska, Piotr Paluch, Karol Lesniewski, Jakub Pudźwa, Kamil Gibczynski, Anita Król, Michal Orczyk

Every year, more and more people start using electronic cigarettes without realizing that these devices can affect their fertility. Further clinical researches are needed to understand the long-term effects of using these devices, because their full impact on reproductive health remains unclear

Medical Science, 2025, 29, e47ms3517

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ARTICLE

Differentiating between oligospermic men and fertile men using aniline blue staining, a marker for sperm chromatin defects

Gülbahar Güzel Erdal, Mahmut Balkan, Diclehan Oral, Mahir Binici, İlyas Yücel, Selahattin Tekeş, Remziye Güzel, Onur Dede, İsmail Yildiz, Mert İpekçi, Zuhal Çankırı

The present study aimed to investigate the relationship between sperm nuclear chromatin condensation and semen parameters in men diagnosed with oligospermia

Medical Science, 2025, 29, e48ms3539

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REVIEW

The impact of extreme sports on mental health: Is "No Risk No Fun" a healthy approach?

Karolina Kalinowska, Aleksandra Paprocka, Urszula Świrk, Paulina Fijałek, Jan Karczmarz, Marika Gutowska, Agnieszka Kosińska, Wiktoria Belcarz, Joanna Orzechowska, Michał Orzechowski

Introduction: This research explores the various aspects of extreme sports, especially their effect on human mental health. Results and discussion: Extreme sports play an essential role in the lives of many people, affecting both their mental and physical health.

Medical Science, 2025, 29, e49ms3536

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The review of modern prospects for the pharmacological treatment of obesity and its complications – The role of GLP- 1, GLP1 / GIP, GLP1 / GIP / GCG receptor agonists

Grzebyk M, Tokarska A, Arnista A, Świątko M, Sosnowski P, Rybak J, Waszczuk A, Kołodziejczyk A, Gawrońska K

Obesity has emerged as a global epidemic and a chronic neuroendocrine condition, significantly contributing to the prevalence of type 2 diabetes and other metabolic disorders

Medical Science, 2025, 29, e50ms3543

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Topical vitamin D as a new acne treatment. A review of the literature

Aleksandra Jonkisz, Seweryn Rozalczyk, Justyna Kowalczewska

Acne vulgaris is a common dermatosis with a complicated and multifactorial basis, occurring in adolescent and adult patients. It is a disease of the pilosebaceous unit

Medical Science, 2025, 29, e51ms3545

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Strategies to mitigate the risk of violence against emergency department staff: A systematic review of the literature

Osamah BinBakheet, Hatim Ali A Alhabi, Fatimah Abdulaziz D Alfaim

Study aim: This study set out to evaluate the impact of intervention programs on the handling of violence against emergency department medical personnel. The study also examined the effects of the therapies on the emergency department staff's goal commitment, attitudes toward and confidence in managing workplace violence, and occupational coping self-efficacy

Medical Science, 2025, 29, e52ms3541

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