Volume 25, Issue 114, August 2021

About the Cover

Background: A new coronavirus (severe acute respiratory syndrome coronavirus 2; SARS-CoV-2) infection began to spread in China, in early December 2019 and has rapidly spread around the globe. While its effects on respiratory symptoms are well recognized, but its effect on thyroid function test is still unclear. We initiated this study with the aim of comparison of thyroid function of Covid-19 affected individuals with that of unaffected individuals. Methods: Clinical examination, laboratory investigation and computed tomography study (CT severity score) of 50 patients with RT-PCR confirmed covid-19 infection who were tested for thyroid function test during their course of hospitalization incovid positive ward in the department of medicine. Other 50 individual who were admitted in covid negative section of the hospital with acute respiratory symptoms during the same period and were found RTPCR negative were also included in the study as control group. Thyroid profile of these two groups were analysed and compared to each other. Result: During the course of COVID-19, of the patients with COVID-19, 74% (37/50) had more-than normal TSH levels, with a p value of < 0.001. As compared with non-COVID-19 pneumonia patients with the serum TSH levels of the patients with COVID-19 were significantly higher.

Table of Contents

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ANALYSIS

Incidence of primary palmar creases variants and their correlation to academic performance in KFU College of medicine-2020: A cross-sectional descriptive study

Mohamed Bahgat Ali, Ahmed Waleed Alrashed, Abdulaziz Emad Alateeq, Ahmed Mamdouh Alkhawfi

Background: Most human palms present have primary creases, but some present only 1-2 creases. PIC model described 21 variants. Previous studies showed great variation in different variants'incidence in different countries and ethnic groups

Medical Science, 2021, 25(114), 1803-1811

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Human enamel analysis in ancient Egyptians and contemporary via LIBS technique

Sayed El Tayeb, Mostafa Z Geith, Mohamed A Harith

Recent studies have shown that chemical and physical approaches are increasingly being used for dental materials analysis and to develop full details and information on the biological circumstances of Humans groupings, prehistoric diets, and the etiology of different illnesses

Medical Science, 2021, 25(114), 1812-1820

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Impact of covid 19 manifestation on thyroid function status in previously euthyroid patients: A cross sectional study

Jaiswal P, Kumar S, Acharya S, Bawankule S, Talwar D, Dhande R, Bagga C, Jugtap G, Verma P, Patel M, Khan S

Background: A new coronavirus (severe acute respiratory syndrome coronavirus 2; SARS-CoV-2) infection began to spread in China, in early December 2019 and has rapidly spread around the globe. While its effects on respiratory symptoms are well recognized, but its effect on thyroid function test is still unclear.

Medical Science, 2021,25(114), 1821-1826

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Efficacy of Acetazolamide in management of idiopathic intracranial hypertension: A systematic review and meta-analysis

Abdulmajeed Albalawi, Alanoud Alharbi, Mawaddah Altaleb, Mohammed Almatrafi, Shuruq Alzahuf, Omayrah Alanzi, Aljawharh Alawad, Asayel Mohammed Bin Saif, Sarah Almuwarraee, Bader Alotaibi, Faisal Almishali, Tarek Kassem, Fatimah Alrajab, Omar Almatrafi, Hezam Alshahrani

Objectives: To investigate the efficacy of acetazolamide in the treatment of idiopathic intracranial hypertension. Methods: We searched PubMed, Scopus, Web of Science, and Cochrane central for relevant published clinical trials

Medical Science, 2021,25(114), 1827-1836

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Abnormal Vaginal Discharge (AVD) among women of Saudi Arabia: Community based cross sectional study

Aqila Homood S Al Shammari, Reem Hamoud S Alshammari, Dnya Saleh A Alanaziy, Atheer Bader F Alanzi

Background: Abnormal vaginal discharge (AVD) is common inwomen during their reproductive life, and if it isn't treated well it may lead to severe complications as pelvic inflammatory disease

Medical Science, 2021,25(114), 1837-1843

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Medical students’ knowledge of child abuse and neglect in Saudi Arabia: A cross-sectional study

Omar A Alshouimi, Musaad N Almusaad, Meshari M Aldawood, Ahmad M Khalaf, Rheem Abdulla Almhizai

Background: Child abuse and neglect are considered one of the problems that affect the child and lead to various psychological problems. Methodology: This was a cross-sectional questionnaire that included all medical students in Saudi Arabia

Medical Science, 2021,25(114), 1844-1850

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RESEARCH

Exploring health care’ experiences on how to inform the patient to get infected with COVID-19: A qualitative study

Ali Gholami, Golbahr Iri, Iraj Ahmadi, Yosof Jamshibeygi, Soudabeh Aloustani, Mohammad Reza Sedi, Milad Borji

Background: COVID-19 disease is a new disease that is very important how informing the patient about it. This study was conducted with the aim of investigating the experiences of the nurses’ staff on how to inform the patient to get infected with COVID-19

Medical Science, 2021, 25(114), 1851-1856

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ANALYSIS

Knowledge, attitudes, and perceptions of dental students towards artificial intelligence in Riyadh, Saudi Arabia

Sanjeev Khanagar, Mohammad Alkathiri, Rakan Alhamlan1, Khalid Alyami, Majed Alhejazi, Ahmed Alghamdi

Introduction: The pace of advancement of artificial intelligence (AI) in dentistry is accelerating rapidly. Thus, it’s very difficult for individuals to conclude that they can fully understand it. The aim of this study was to assess the knowledge, attitudes, and perceptions of dental students in Riyadh, Saudi Arabia towards (AI).

Medical Science, 2021, 25(114), 1857-1867

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Prediction of psychosocial adjustment based on Covid-19 stress, Covid-19 anxiety, acculturation, and perceived discrimination in Iranian students living abroad

Dorsa Baharloo, Maryam Bakhtiari, Maryam Aslzaker, Abbas Masjedi Arani

Introduction: The prevalence of pandemic has led to an increment of psychological problems, moreover decrement in psychosocial adjustment. These conditions may be more severe for immigrants

Medical Science, 2021, 25(114), 1868-1877

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CASE REPORT

Fatal HELLP syndrome in pregnancy: A sequelae of Long COVID?

Ojas Mahajan, Dhruv Talwar, Sunil Kumar, Arpita Jaiswal, Sparsh Madaan, Shivam Khanna, Divit Shah

The coronavirus disease resulted by infection with severe acute respiratory syndrome-Coronavirus 2 (SARS-CoV-2) was initiated in China in during the end of 2019 and spread exponentially as a global health Pandemic

Medical Science, 2021, 25(114), 1878-1881

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ANALYSIS

Sensitivity, specificity, positive and negative predictive value of nasopharyngeal and throat swabs in detection of Sars-Cov-2 among infected patients

Nuha Alsaleh

Background: In the care of patients, early and accurate respiratory virus identification (RRI) is critical. We have previously demonstrated the feasible and responsive self-recollected nasal swabs (NS) to detect RV, but the additive advantages of the self-collected throat swabs are unknown

Medical Science, 2021, 25(114), 1882-1886

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CASE REPORT

A novel, non-invasive approach in management of inflammatory dentigerous cyst in young child: A case report and review of literature

Neeta Padmawar, Viddyasagar Mopagar, Vinay Vadvadgi, Sourabh Joshi, Jayshree Vishwas, Meghna Padubidri

Introduction: Developmental and inflammatory are the two variants of dentigerous cyst which is the second frequently reported odontogenic tumour. Displacement, mobility of tooth, swelling are the clinical characteristics

Medical Science, 2021, 25(114), 1887-1893

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ANALYSIS

The hemodynamic variability after transverse abdominal block in lower abdominal surgeries

Maytham M Kadhim, Khaleel Jummah Kareem, Muthana Abdul Kadhim Saad

Objective: Investigate the effects of pre-incisional bilateral transversus-abdominis plane block on intraoperative hemodynamics and analgesia in patients undergoing general anesthesia for elective lower abdominal surgery

Medical Science, 2021, 25(114), 1894-1899

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RESEARCH

Evaluation of anticancer activity of Paclitaxel (PLT) and D-L Sulfarophane (SFN) as natural vegetable derivative against colon cancer cell line: In vitro study

Ali Hassan A Ali, Abdulrahman M Almalki, Talal A Alharbi, Musaad H Alanzy, Muath A Alghuwainem, Fahd M Alanazi, Nasser I Alshumaymiri, Aly Fahmy Mohamed

Paclitaxel (PTx) and D-L Sulforaphane (SFN) natural derivatives could inhibit many types of cancerous cells proliferation through apoptosis and autophagy. Toxicity of PTx and SFN to Caco-2 cells was concentration dependent using MTT assay

Medical Science, 2021, 25(114), 1900-1909

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CASE REPORT

Post covid fatal antibody dependent enhancement of dengue infection in a young male: Double trouble

Iqbal Beig, Dhruv Talwar, Sunil Kumar, Sourya Acharya, Vidyashree Hulkoti

Antibodies against Dengue virus (DENV) have been postulated to act against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) which might reduce the severity of COVID19 in a patient who previously had dengue fever

Medical Science, 2021, 25(114), 1910-1914

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Multimodal physiotherapy program in treatment of post-operative femoral condylar stiffness: A case report

Mansi Karwa, Tajuddin Chitapure, Rinkle Malani

Post traumatic restricted range of motion in knee joint is termed as knee stiffness and is the most significant complication after intra articular or extra articular injury

Medical Science, 2021, 25(114), 1915-1919

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RESEARCH

The protective effect of icariin in testosterone-induced benign prostatic hyperplasia in rats via suppression of macrophage infiltration

Thikryat Neamatallah, Basma G Eid

Benign prostatic hyperplasia (BPH) is a disorder that affects males at the age of 40. Icariin (ICA) is a flavonoid reported to treat impotence, atherosclerosis, and osteoporosis

Medical Science, 2021, 25(114), 1920-1930

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CASE REPORT

Corpus alienum – A rare case of tablespoon in the rectovesical pouch

Lukas Cuchrac, Jana Simonova, Jozef Firment, Robert Simon, Janka Vaskova

Ingestion of foreign bodies, mostly common household utensils, is not unusual in adults, with higher prevalence in individuals who are intoxicated, incarcerated, or mentally handicapped

Medical Science, 2021, 25(114), 1931-1937

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ANALYSIS

Nanoparticles loaded with garden cress (Lepidium sativum L.) extract induce apoptosis in breast cancer

Al-Abbas Nouf S, Shaer Nehad A

Garden cress herb (Lepidium sativum L.) extract has recently gained attention in research over the past years. Many of the published research articles discuss are its use in treating different types of cancer

Medical Science, 2021, 25(114), 1938-1946

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A prospective comparative study between prewarming and cowarming to prevent intraoperative hypothermia in spinal anaesthesia

Aruna V Chandak, Krishnendu S, Vijay Chandak, Vivek Chakole

Introduction: Temperature is one of the important parameter to be monitored in anaesthesia. Regional anaesthesia impairs thermoregulation as in general anaesthesia. There are several studies comparing different techniques to prevent intraoperative hypothermia

Medical Science, 2021, 25(114), 1947-1954

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Assessment of care needs of the elderly living in Kermanshah province in 2020

Hamid Taghinejad, Alireza Abdi, Sattar Kikhavani, Akbar Ebrahimi

Introduction: The elderly often has complex and unknown needs that we have not yet been able to fully recognize in accordance with international standards in the country

Medical Science, 2021, 25(114), 1955-1962

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Epidemiological estimation incidence and mortality from cancer of the larynx in Ukraine and Europe

Mazur Olha, Plaksyvyi Oleksandr, Chornenka Zhanetta, Biduchak Anzhela

Background: Cancer incidence among the world's population has a steady upward trend. Malignant tumours of the larynx are the most frequent in the structure of oncological morbidity of otolaryngological organs and occupy a leading position

Medical Science, 2021, 25(114), 1963-1970

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Prevalence of premenstrual syndrome among medical students in King Faisal University in Alahssa-Saudi Arabia

Fatimah Alkhamis, Layla Abd Alaziz Almzraq, Zahraa Khaled Alshayeb, Zainab Yaseen AL-Jaziri

Background: Premenstrual syndrome (PMS) is a collection of excruciating psychological and behavioral symptoms with or without physical (somatic) symptoms that are not caused by organic disease

Medical Science, 2021, 25(114), 1971-1983

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Knowledge and attitudes toward Do-Not-Resuscitate decisions among medical students in Jeddah, Kingdom of Saudi Arabia

Haytham A Abbas, Asrar A Al Ahmadi, Osama Hameed G Alharby, Rahf Ayman H Aman, Elgawhara Faisal Awad Mohamed, Nawaf Abdullah K Tawlah

Objective: Do-Not-Resuscitate (DNR) order is made in certain situations where patients are terminally ill and CPR is not predictable to succeed. Furthermore, many controversial ethical challenges arise in the management of death because of patients’ religious and cultural background.

Medical Science, 2021, 25(114), 1984-1991

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Awareness of Saudi population about sudden cardiac death in Arar, Northern Saudi Arabia

Abdelrahman Mohamed Ahmed Abukanna, Manar Sulaiman M Alshammari, Amal Qatif J Alashjaee, Faya Awad S Alshammari, Taghreed Arar S Alruwaili

Background: Sudden cardiac death (SCD) is death due to cardiovascular reasons in an individual with or free from foregoing cardiac disease. Objective: To explore the public awareness concerning the reasons, risk factors, and management of sudden cardiac arrest (SC) in Arar city, Northern Saudi Arabia

Medical Science, 2021, 25(114), 1992-2000

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Knowledge, attitude, and practices of healthcare workers in Riyadh, Saudi Arabia regarding the use of face masks for limiting the spread of coronavirus disease

Sulaiman Al Shammari, Abdulrahman Alrasheed, Abdulrahman Aljurayyan, Muath Aljufayr, Shatha Alghaihb, Abdullah Alelaiwi

Background: The World Health Organization (WHO) declared Coronavirus disease 2019 (COVID-19) a global pandemic in March 2020. Healthcare workers (HCWs) are at a higher risk of infection with the virus than other individuals

Medical Science, 2021, 25(114), 2001-2010

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Knowledge and attitudes of family physicians towards coronavirus disease 2019 infection burden: A cross-sectional study

Molook Alotibi, Ola Alqudah, Safa Alqudah

Objectives: Investigate the knowledge and attitudes of family physicians towards coronavirus disease (COVID-19). Methods: Data were collected from family medicine residents at King Fahd Medical City in Riyadh, Saudi Arabia, using an online questionnaire that assessed demographics, knowledge about COVID-19, and attitudes towards the disease

Medical Science, 2021, 25(114), 2011-2018

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Acknowledging popular misconceptions about scabies in Aseer region, Saudi Arabia

Ahmad ALQarni, Emad Bahashwan, Albaraa Alwabel, Ebtisam Almosawed, Adel Alfaifi, Saleh Ahmed Alshaikhi

Background: Human Scabies is an intensely itchy dermatological disease caused by the mite Sarcoptesscabiei hominis. Scabies is a problem of all ages, races, and all socioeconomic groups are susceptible. It is influenced by many environmental factors

Medical Science, 2021, 25(114), 2019-2024

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CASE REPORT

An undue guest of thrombotic thrombocytopenic purpura with acute myeloid leukemia in an elderly patient with Crohn’s disease

Khairul Najmi Muhammad Nawawi, Sopian Abdul Wahab, Wong Zhiqin, Nor Rafeah Tumian, Raja Affendi Raja Ali

Thrombotic thrombocytopenic purpura and acute myeloid leukemia are rarely associated with Crohn’s disease. Early recognition of these conditions with timely referral to hematologist is paramount

Medical Science, 2021, 25(114), 2025-2029

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ANALYSIS

Prevalence of skin problems and its health impact among adolescent school children in Majmaah, Saudi Arabia

Mansour K Alzahrani, Mubarak Ali M Almanaah, Ahmed Abdullah M Alabdulatif, Salman Muqhim N Alshammari, Ahmad Mazroa Almazroa

Background: Adolescents suffer the consequences of sudden spurt in their growth and development and one of them is the multitude of skin disorders. This creates a sense of physiological and psychological insecurity which hinders their day to day activities including academic progress

Medical Science, 2021, 25(114), 2030-2037

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CASE REPORT

Paranasal Mucormycosis in immunocompromised host (Early diagnosis is the key)

Bushra Al-qurashi, Ismail Khan Mohammed, Omer Al-nashiwaaty, Moataz Al-knawy

Mucormycosis is an emergent life threatening fungal infection that has potential risk of dissemination with significant morbidity and mortality rate particularly among patient with altered immune status.

Medical Science, 2021, 25(114), 2038-2042

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Unusual presentation of lupus erythematous profundus in a young female treated by intralesional trimacinolone and oral methotrexate: A case report

Awadh Alamri, Sahal Samarkandy, Hatim Al-Maghraby, Hassan Huwait, Samir Alamri, Hebah Alahwal, Mazen Dajam

Systemic lupus erythematosus is a chronic autoimmune condition that can attack almost any organ. In fact, its clinical manifestations and serological abnormalities are the most diverse one among other autoimmune diseases.

Medical Science, 2021, 25(114), 2043-2047

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ANALYSIS

Prevalence of eye refractive errors, strabismus, and amblyopia among children referred to eye clinic in secondary hospital, Majmaah city, Saudi Arabia

Rashed Almutairi, Khalid M Alabdulwahhab, Mohammad S Ahmad, Riyaz A Shaik, Saleh Ali Alribi

Introduction: Refractive errors are a preventable cause of blindness in children, resulting in visual disabilities. This study was carried out with an objective to determine the prevalence of common eye refractive errors among children aged between (3 to 15) years

Medical Science, 2021, 25(114), 2048-2055

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Knowledge and perception of bariatric surgery among physicians at King Saud University Medical City, Riyadh, Saudi Arabia

Ahlam F. Alotaibi, Ayan Ahmed Hassan, Wael Saleh Almogheer, Noura Abouammoh, Afnan S. Younis

Background: Bariatric surgeries were among the common solutions provided by nutritionists and physicians to avoid obesity complications, especially among chronic diseases patients

Medical Science, 2021, 25(114), 2056-2067

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RESEARCH

A focus on abdominal sepsis: The problem of prognostic markers

Kryvoruchko Igor Andreevich, Sykal Nikolaj Alexandrovich, Yevtushenko Olexander Vasyliovych, Riabtsev Roman Sergiiovych

Background: Determining the prognosis of mortality from abdominal sepsis in patients with one surgical intervention is an urgent problem. Methods: It study was based on data from comparing of severity scores in 136 patients with abdominal sepsis

Medical Science, 2021, 25(114), 2068-2076

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ANALYSIS

Hypoglycemic and protective effects of Boswellia carterii against functions and structures of thyroid gland in rat model of type 2 diabetes

Dalia Domiaty, Anoud Althagafi, Muna Alamoudi, Haleema Al-Nahary, Saleh Fouaz Bakrshoom

Boswellia carterii extract has many beneficial pharmacological activities and various medicinal utilization. The scientific data about its effects on thyroid functions of type 2 diabetes is limited

Medical Science, 2021, 25(114), 2077-2087

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The prevalence of obsessive-compulsive disorder and symptoms among medical students: A perspective study from Riyadh, Saudi Arabia

Ahmad M Khalaf, Salman K Alshuaibi, Fahad B Bin Abbas, Saleh A Alwadie, Nader Alrahili, Fareha Bano, Razique Anwer

Background: Obsessive-compulsive disorder (OCD) is a neuropsychiatric disorder portrayed by obsessions and compulsions that are distressing, tedious, or cause significant impedance

Medical Science, 2021, 25(114), 2088-2095

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Efficacy of Rhubarb root extract on quality of life in patients with systolic heart failure: A randomized placebo controlled study

Zohre Gholami, Mohsen Bahrami, Mohammad Kamalinejad, Hassan Ahangar, Tara Reshadmanesh, Sepehr Gohari

Introduction: This study aimed to investigate the role of Rheum palmatum on quality of life and cardiac function in patients with systolic heart failure. Material and Method: This was a parallel double-blind, placebo-controlled trial study from April to August 2019.

Medical Science, 2021, 25(114), 2096-2104

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CASE REPORT

Giant form of Molluscum Contagiosum: A case report

Eman M Bamoosa, Malak F Alshaebi, Khalid A Al hawsawi

Molluscum Contagiosum (MC) is a common, viral skin infection characterized by small papules that are spread all over the body and is resolved spontaneously within a year. In this article we present a 65-year-old male, with an atypical appearance of MC

Medical Science, 2021, 25(114), 2105-2108

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