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Volume 30, Issue 175, September 2026 (Forthcoming Issue)

About the Cover

Alzheimer's disease is the most common form of dementia in the world, affecting tens of millions of people. Neuroinflammation is now known to be an important part of the process of Alzheimer's disease (AD) developing. In the past, it was thought of as a secondary byproduct of amyloid-beta (Aβ) plaque and tau neurofibrillary tangle accumulation, but it is now understood to be a central and early-acting pathological mechanism in AD progression. This review looks at how the brain and nervous system are affected by inflammation.


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REVIEW

Neuroinflammation in Alzheimer's disease: current evidence and therapeutic targets - Part II

Izabela Ślusarczyk, Szymon Uszak, Adrianna Chachuła, Natalia Kruk, Jan Olszewski, Julia Rojek, Wojciech Szlajss, Patrycja Jędrzejewska, Tomasz Szczawiński, Daria Wieczorek

Alzheimer's disease is the most common form of dementia in the world, affecting tens of millions of people. Neuroinflammation is now known to be an important part of the process of Alzheimer's disease

Medical Science, 2026, 30, e180ms3904

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Clinical applications of platelet-rich fibrin (PRF) in dentistry and oral surgery: A review of the literature

Daria Wieczorek, Adrianna Chachuła, Natalia Kruk, Izabela Ślusarczyk, Jan Olszewski, Julia Rojek, Patrycja Jędrzejewska, Szymon Uszak, Wojciech Szlajss, Tomasz Szczawiński

Platelet-rich fibrin (PRF) is a biomaterial obtained from patients themselves. That made it an essential material in oral and maxillofacial surgery due to its effectiveness in stimulating tissue repair

Medical Science, 2026, 30, e181ms3915

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The Most Common Complications Associated with Endoscopic Endonasal Transsphenoidal Surgery for Pituitary Tumors: A Review

Justyna Kowalczewska

Endoscopic endonasal transsphenoidal surgery (EETS) is currently the preferred surgical technique for the treatment of most pituitary tumours. Its advantages include wide, panoramic access

Medical Science, 2026, 30, e182ms3966

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Development of postoperative obstructive symptoms in patients with Hirschsprung disease

Paula Szymańska, Ewelina Knapczyk, Maria Smółka, Patryk Omylak, Aleksandra Podraszka, Przemysław Prokop, Zuzanna Wróbel

Hirschsprung disease (HSCR) is a rare congenital disorder of the intestine, typically diagnosed in neonates presenting with delayed passage of meconium and signs of bowel obstruction.

Medical Science, 2026, 30, e183ms3918

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The use of Botulinum toxin type A in various medical fields: A systematic review

Natalia Sak, Kamil Kraziński, Ali Kraziński, Karolina Jońska, Damian Broda, Wiktoria Mikulska, Julia Kałużna, Kamila Tasior, Oliwia Dziewięcka, Wojciech Ziębka, Katarzyna Sikora, Julia Wilanowska, Aleksandra Broda

Clostridium botulinum bacteria produce neurotoxin called Botulinum toxin type A. The mechanism of action of Botulinum toxin is to block the release of the neurotransmitter.

Medical Science, 2026, 30, e184ms3932

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Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: Understanding Procedural Risks and Complications

Justyna Kowalczewska

Chronic subdural hematoma (cSDH) is frequently diagnosed in older patients, and the incidence continues to increase as the population ages, antithrombotic therapy becomes more common, and diagnostic imaging is more widely available

Medical Science, 2026, 30, e185ms3973

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The Role of Selected Dietary Supplements (Vitamin D, Creatine, Folic Acid, and Omega-3 Fatty Acids) in the Management of Depressive Disorders: A Narrative Review

Zuzanna Knap, Marcelina Zielińska, Przemysław Iwański, Julia Kałużna, Ali Kraziński, Julia Mrowińska, Aleksandra Mazur, Natalia Grzywacz, Iga Chalimoniuk, Anna Hejman

Depression is one of the most disabling conditions in the world, and many patients do not achieve full remission with standard treatments. There has been increasing interest in dietary supplements as potential adjuncts

Medical Science, 2026, 30, e186ms3972

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The Role of Physical Activity and Exercise Training in Patients Undergoing Hemodialysis

Przemysław Iwański, Zuzanna Knap, Natalia Grzywacz, Anna Hejman, Aleksandra Mazur, Iga Chalimoniuk, Julia Mrowińska, Ali Kraziński, Julia Kałużna, Marcelina Zielińska

Purpose: Patients undergoing hemodialysis experience muscle weakness and limited exercise ability, making it difficult to perform everyday activities. This article discusses the impact of physical activity and exercise training

Medical Science, 2026, 30, e187ms3970

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Diet and Age-Related Macular Degeneration: A view on the relationship between dietary patterns, dietary elements supplementation, and Age-Related Macular Degeneration

Wojciech Bogacki, Patrycja Pudzisz, Dawid Przybylski, Stanisław Brożyna, Karolina Szamocka, Aleksandra Koszałka, Katarzyna Frączek, Karolina Bińkowska-Chęć

Age-Related Macular Degeneration (AMD) is a degenerative disorder of the human retina. The pathophysiological essence of AMD is closely related to senescence of retinal tissues and the accumulation of uncleared cellular waste

Medical Science, 2026, 30, e188ms3942

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Factors Influencing the Postoperative Course After Tooth Extraction: A Review of the Literature

Patrycja Jędrzejewska, Adrianna Chachuła, Natalia Kruk, Szymon Uszak, Wojciech Szlajss, Daria Wieczorek, Izabela Ślusarczyk, Jan Olszewski, Julia Rojek, Tomasz Szczawiński

Tooth extraction is common. The postoperative course depends on many factors. The most common implications are alveolar osteitis (dry socket), infection, bleeding, swelling, trismus, and nerve injury

Medical Science, 2026, 30, e189ms3939

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Diagnosis and Therapeutic Management of Acute Appendicitis During Pregnancy: A Contemporary Narrative Review

Martyna Olszyna, Cezary Jasiński, Barbara Durma, Szymon Siudak, Oliwia Dudek, Daniel Glinka, Zuzanna Domagała, Maria Ryśkiewicz, Daria Kózka, Agata Choroś

Acute appendicitis (AA) remains the most common non-obstetric cause of surgery in pregnant women. Although significant advances have been made in diagnostic imaging and surgical techniques in recent years

Medical Science, 2026, 30, e190ms3956

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CASE REPORT

Unmasking a Contralateral Pituitary Neuroendocrine Tumor After Resection of a Decoy Lesion: A Case Report

Justyna Kowalczewska

Multiple pituitary adenomas (MPA) are a rare condition characterized by the presence of 2 or more histologically and/or radiologically distinct pituitary tumors in a single patient.

Medical Science, 2026, 30, e191ms3982

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REVIEW

Migraine and neurodevelopmental disorders: shared mechanisms linking autism and attentiondeficit/ hyperactivity disorder

Aleksandra Frączek, Angelika Klaudia Juszczyk, Gabriela Kaptur, Anna Mierzwa, Sylwia Julia Pietrajtis, Kinga Zofia Rosołowska, Anna Wrona

Background: Migraine is a neurological disorder that often occurs alongside psychiatric and neurodevelopmental conditions. Evidence of an association between migraine and both autism spectrum disorder (ASD)

Medical Science, 2026, 30, e192ms3981

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Exercise snacks as a time-efficient approach to improving health and physical activity

Aleksandra Frączek, Angelika Juszczyk, Gabriela Kaptur, Anna Mierzwa, Sylwia Pietrajtis, Anna Wrona, Kinga Rosołowska

Background: Sedentary behavior and insufficient physical activity are common problems and are associated with an increased risk of obesity and cardiometabolic disease.

Medical Science, 2026, 30, e193ms3983

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Cancer screening adherence after the COVID-19 pandemic: Global challenges and outcomes

Julia Rojek, Jan Olszewski, Szymon Uszak, Patrycja Jędrzejewska, Tomasz Szczawiński, Izabela Ślusarczyk, Wojciech Szlajss, Daria Wieczorek, Natalia Kruk, Adrianna Chachuła

Background/Purpose: The spread of the novel Coronavirus (SARS-CoV-2) has caused major problems for cancer screening services around the world. This has led to delayed diagnoses, more advanced stages of cancer at diagnosis

Medical Science, 2026, 30, e194ms3941

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Management of Mitten-Glove Hand Deformity in Recessive Dystrophic Epidermolysis Bullosa: A Narrative Review of Surgical, Rehabilitation, and Adjunctive Treatment Strategies

Mikołaj Cezary Krajewski, Jakub Papierz, Katarzyna Cybulska, Julia Banaszczyk, Stanisław Janczarski, Gabriela Królczyk, Aleksandra Pietrzyk

Introduction and Objective: Recessive dystrophic epidermolysis bullosa (RDEB) is a serious hereditary condition (mutations within the COL7A1 gene) characterized by chronic inflammation

Medical Science, 2026, 30, e195ms3960

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Creative Commons License

© The Author(s) 2026. Open Access. This article is licensed under a Creative Commons Attribution License 4.0 (CC BY 4.0).