Volume 27, Issue 134, April 2023

Effect of copper-doped phosphate glass on dental resin material: In vitro study

Ahmed B EI Okl¹, Samar H Abuzinadah^2♦, Mohamed Aboshama³, Rayyan A Kayal⁴, Abdulrahman J Alhaddad⁵, Samah M Awad⁶, Osamah Alsulimani⁷, Salem K Aloubathani⁸, Abdu M Abuhubayrah⁸, Gehan A El Olimy⁹

¹Professor of Removable Prosthodontics, Removable Prosthodontic Department, Faculty of Dental Medicine, Al-Azhar University, Asuit, Egypt
²Assistant Professor and Consultant of Restorative Dentistry, Restorative Dentistry Department, King Abdul-Aziz University, Faculty of Dentistry, Jeddah, Saudi Arabia
³Lecturer of Removable Prosthodontics, Removable Prosthodontic Department, Faculty of Dental Medicine, Al-Azhar University, Asuit, Egypt
⁴Associate Professor and Consultant of Periodontics, Department of Periodontology, King Abdulaziz University, Faculty of Dentistry, Jeddah, Saudi Arabia
⁵Associate Professor and Consultant of Prosthodontics, Oral and Maxillofacial Prosthodontics Department, King Abdul-Aziz University, Faculty of Dentistry, Jeddah, Saudi Arabia
⁶Assistant Professor of Medical Microbiology and Immunology, Clinical Microbiology and Immunology department, National Liver Institute, Egypt
⁷Assistant Professor and Prosthodontist, Oral Diagnostic Sciences Department, King Abdul-Aziz University, Faculty of Dentistry, Jeddah, Saudi Arabia
⁸General Practitioner Dentist, King Abdul-Aziz University, Faculty of Dentistry, Jeddah, Saudi Arabia
⁹Assistant Professor of Dental Biomaterial, Dental Biomaterial department, Faculty of Dentistry, Tanta University, Egypt

^♦Corresponding author
Assistant Professor and Consultant of Restorative Dentistry, Restorative Dentistry Department, King Abdul-Aziz University, Faculty of Dentistry, Jeddah, Saudi Arabia

ABSTRACT

Background: This study aims to incorporate the oxide copper particles with phosphate-based glass fibers (PGF) into a poly methyl methacrylate (PMMA) resin material and investigate its antimicrobial effect. Material and Methods: (CuO)-containing PGF added to the PMMA resin (5, 10, 20 and 30 wt %). The antimicrobial activity was measured in the lab using the direct contact test against Klebsiella pneumonia, Staphylococcus aureus and Candida albicans. The agar diffusion test was used to measure the release of the (CuO). The results were analyzed and compared using a one-way analysis of variance, followed by the Student-Newman-Keuls-multiple-comparisons test. Differences were considered significant when the p-value was less than 0.05. Results: Compared to the control groups, a significant drop in K. pneumonia, S. aureus, and C. albicans was observed with all antimicrobial agent ratios. Conclusion: Adding (CuO)-containing PGF to PMMA dental resins provided a high antimicrobial effect against K. pneumonia, S. aureus bacterial and Candida species.

Keywords: Dental resin, PMMA, Copper Oxide (CuO), Phosphate glass fiber (PGF), Antimicrobial

Medical Science, 2023, 27, e190ms2987

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DOI: https://doi.org/10.54905/disssi/v27i134/e190ms2987

Published: 15 April 2023