Volume 28, Issue 145, March 2024

About the Cover

Background: In Saudi Arabia, sickle-cell disease is among the most prevalent hematologic hereditary illnesses. In SCD patients, vascular-occlusive pain crises are a common reason for emergency room visits, and patients' suffering may go untreated. This research offers a systematic literature review of the current treatments for acute pain crises in SCD patients. Method: The authors examined five scientific databases—MEDLINE, PubMed, CENTRAL, CINAHL, and Web of Science—to locate published works through 2023. For every database, a comprehensive search strategy was developed using MeSH keywords. The phrases opioids, anemia, sickle cell, double-blinded, randomized controlled study, acute pain, and clinical trial are used. Results: Six full-text articles with 424 patients were included for our review out of the 201 articles initially gathered from databases. Duplication was removed, and the articles were assessed against inclusion criteria. Of the included studies, three were conducted in the United States, one in Connecticut, one in Maryland, and one in Canada. Using guidelines for higher opioid doses for acute painful episodes in SCD patients was related to better pain outcomes and fewer hospitalizations. According to current standards, patients with SCD should get opioid analgesia within 30 minutes of being triaged.

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REVIEW

Opioids used to manage acute pain crisis in adults with sickle cell disease in emergency department: Systematic review

Ahmed Saad Aleid, Haitham Mohammed Alhussain, Sultan Suwailem Alghannami, Yazeed Ibrahim Altheiban

Background: In Saudi Arabia, sickle-cell disease is among the most prevalent hematologic hereditary illnesses.

Medical Science, 2024, 28, e8ms3294

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Effect of educational intervention on quality of life of asthma patients: A systematic review

Sara Shahid, Gohar Jaan, Amna Nadeem, Javaria Nadeem, Kiran Fatima, Amna Sajjad, Fatima Javed, Maryam Mazhar, Muhammad Zahid Iqbal

Background: Asthma is a chronic inflammatory disorder that causes shortness of breath, wheezing and chest tightness. It affected 262 million people globally in 2019 and resulted in 455,000 deaths

Medical Science, 2024, 28, e9ms3300

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CASE REPORT

Gangrene sigmoid volvulus: A rare case report from Vietnam

Phu V Pham, Hoa T Tran, Duy HN Nguyen, Truong DA Nguyen, Lap B Duong

Background: Sigmoid volvulus is a gastrointestinal condition and a medical emergency that occurs when a segment of the colon twists upon its mesentery, leading to bowel obstruction and gangrene of the intestine

Medical Science, 2024, 28, e10ms3297

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ARTICLE

Impact of sociodemographic determinants on control in hypertension patients: A community pharmacy-based cross-sectional study

Muhammad Zahid Iqbal, Naeem Mubarak, Sara Shahid, Minahil Akram, Shaikh Muhammad Usama Latif, Ayesha Nawaz, Afshan Abdul Shakoor, Maria Asghar, Ambreen Ijaz, Muskan Irfan, Gohar Jaan, Amna Nadeem, Fateh Sher, Neha Fatima, Tooba Farooq

Background: Hypertension is one of the significant public health issues around the globe. Controlling blood pressure is imperative to stop the progression of hypertension in complicated cardiac problems

Medical Science, 2024, 28, e11ms3301

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REVIEW

Investigating the influence of patient demographics on the utilization of Complementary and Alternative Medications (CAM) for treating various lifestyle diseases in community and hospital pharmacies: A comprehensive literature review

Muhammad Zahid Iqbal, Neha Fatima, Sadia Ahmad, Tooba Farooq, Muntaha Gull Shahid, Rabia Zaka, Nisha Noor, Rameen Asif, Rabia Saleem, Nageen Ramzan, Ayesha Zulfiqar

Background: Alternative and complementary medicine (CAM) is extensively utilized worldwide due to its potential in relieving both psychological and physical conditions

Medical Science, 2024, 28, e12ms3298

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ARTICLE

Cross-cultural adaptation, validity, and reliability of the Arabic version of the shoulder disability questionnaire

Abdulrahman M Hakami, Fahad H Alshehri, Hosam Alzahrani, Rania Almeheyawi, Ibrahim S Aljulaymi, Hatem H Allam, Lamia K Elsayyad, Marwa M Eid

Background: Following low back and knee discomfort, shoulder pain (SP) is the third most common musculoskeletal problem, with an estimated global prevalence of 1.0%–4.8%.

Medical Science, 2024, 28, e13ms3306

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Prevalence and impact of burnout in Emergency Department nurses; a multicenter study in Riyadh, Saudi Arabia

Tawfiq Almezieny, Abdulmajeed Alashaikh, Reema Alnasser, Saad Dammas, Nouf Alsubaie, Yara Alhusaini, Taif Alotaibi

Background: Burnout among healthcare professionals, particularly nurses, is a significant concern globally. Emergency department (ED) nurses, operating in high-stress environments, may be particularly vulnerable to burnout

Medical Science, 2024, 28, e14ms3304

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Post corrosive ingestion in pediatrics; precaution and awareness; retrospective hospital-based study

Muhannad Almajed, Yasir Albarrak, Wadha Aldosari, Musa Alkhormi, Ahmed Alawfi, Husam Islam

Background: Both acidic and alkaline products that are corrosive when ingested might result in major complications

Medical Science, 2024, 28, e15ms3295

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Correlation between halitosis and self-reported halitosis in patients with personality type A and B

Hamid Reza Khalighi, Zahra Yazdani, Saeid Ghasemi, Fahimeh Anbari

Background: It has been shown that the patient's personality type can affect the outcome of dental diagnosis and treatment.

Medical Science, 2024, 28, e16ms3281

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The influence of sociodemographic factors on the control of blood glucose levels among diabetic outpatients visiting various community pharmacies in Lahore

Muhammad Zahid Iqbal, Naeem Mubarak, Noor Fatima, Laiba Zaheer, Aneeza Safdar, Iqra Mansoor, Neha Fatima, Zonia Iqbal, Amna Razzaq, Tooba Farooq, Sadia Ahmad, Fizzah Saleem, Maham Maqsood, Maham Bukhari, Nisha Noor, Muhammad Abuzar Khan

Background: Diabetes mellitus poses a significant global health challenge, necessitating effective blood glucose control to prevent complications. Sociodemographic factors influence diabetes management

Medical Science, 2024, 28, e17ms3311

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Predicting and quantifying seated comfort while using two different seat cushioning materials

Hatem H Allam, Fahad Hadi Alshehri, Alsufiany Muhsen, Ohood A Al-sufyani, Smah S Alkhalidi, Sundous F Bokhari, Mashael H Alwagdani, Arwa S Althuwaybi, Amani H AlGhamdi, Alanoud T Alotaibi, Rimaz S Aljohani, Sumayah M Alshomrani, Ashwag M Althobaiti, Lamiaa K Elsayyad

Background: Adequate chair design and comfort are essential to the educational environment. Aim: The current study investigated the effect of cushion characteristics on student comfort during class time, aiming to increase the students' comfort and positively affect their academic gain

Medical Science, 2024, 28, e18ms3313

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Design and fabrication of metoclopramide fast dissolving films by using combined natural and synthetic polymers, and in vitro evaluation

Muhammad Abid Mustafa

Objective: Formulation aims to develop a film that dissolves quickly for advanced solid dosage forms in order to increase the drug's bioavailability and enhance its action.

Medical Science, 2024, 28, e19ms3303

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REVIEW

Management of Gestational Diabetes Mellitus in Middle East and North Africa: Systematic review

Hattan Dagestani, Ali Alamri, Faisal Bandar Alshammari, Samiyah Marzouq Alanazi

Background: Overweight and high parity are two of the many risk factors for gestational diabetes mellitus that affect women in Saudi Arabia

Medical Science, 2024, 28, e20ms3312

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ARTICLE

Cardiovascular Disease prevention: Assessing knowledge and lifestyle choices through a population survey

Priya Devi, Anwar Ali Jamali, Komal, Adesh Kumar, Kamlesh Kumar, Iftikhar Ali

Cardiovascular diseases (CVDs) are a leading cause of mortality globally. This cross-sectional study assessed the knowledge and lifestyle behaviors related to CVD prevention in the general population

Medical Science, 2024, 28, e21ms3308

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Osteoporosis prevention habits: Investigating physical activity and dietary practices

Priya Devi, Anwar Ali Jamali, Adesh Kumar, Komal, Iftikhar Ali, Kamlesh Kumar

Osteoporosis poses a significant public health burden due to population aging. This cross-sectional study aimed to investigate osteoporosis prevention habits regarding physical activity and dietary practices among 210 adults

Medical Science, 2024, 28, e22ms3309

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REVIEW

Systematic review of the selfmedication practice among medical students across South Asian countries

Sara Shahid, Komal Zulfiqar, Khadija Butt, Iram Yousaf, Alvina Shabbir, Eman Zaheer, Neha Fatima, Umair Amjad, Arooj Majeed, Wasiq Ali, Tasmia Munir, Mahnoor Qaiser, M Sohaib Sultan Sabri, Muhammad Zahid Iqbal

Background: Self–medication is the act of using pharmaceuticals without consulting a doctor, though a universal definition is still problematic.

Medical Science, 2024, 28, e23ms3314

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Role of Artificial Intelligence in polypharmacy and medication nonadherence in Saudi Arabia

Husna Irfan Thalib, Sariya Khan, Dalaa Sheikh Saleh, Asim M Alshanberi, Yosra Z Alhindi, Safaa M Alsanosi

Polypharmacy and medication nonadherence are growing global challenges in healthcare, especially among the older population

Medical Science, 2024, 28, e24ms3321

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Safety and efficacy of Mini- Gastric Bypass surgery: A systematic review study

Abdulaziz Khaled Alrasheed, Alwaleed Sami Alotaibi, Musab Mousa Al-Masud

Background: Mini-gastric bypass (MGB) surgery is a successful and secure method for losing weight. It provides lasting weight loss with the possibility of revision or reversal

Medical Science, 2024, 28, e25ms3317

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