Volume 29, Issue 159, May 2025

Lycopene in Prevention and Treatment of Civilization Diseases: A Literature Review

Aleksandra Paprocka^1♦, Karolina Kalinowska², Urszula Świrk³, Paulina Fijałek⁴, Jan Karczmarz⁵, Marika Gutowska⁶, Agnieszka Kosińska⁷, Wiktoria Belcarz⁸, Joanna Orzechowska⁹, Michał Orzechowski¹⁰

¹Jan Mikulicz-Radecki University Clinical Hospital, Borowska 213, 50-556 Wroclaw, Poland
²Health Care Team of the District Hospital In Sochaczew, Batalionów Chłopskich 3/7, 96-500 Sochaczew, Poland
³Independent Public Health Care Facilities in Przasnysz, Dr. Wojciech Oczko Hospital, Sadowa 9, 06-300 Przasnysz, Poland
⁴Southern Hospital, Rotmistrza Witolda Pileckiego 99, 02-781 Warsaw, Poland
⁵Southern Hospital, Rotmistrza Witolda Pileckiego 99, 02-781 Warsaw, Poland
⁶Józef Struś Multi-Specialist Municipal Hospital, Szwajcarska 3, 61-285, Poznań
⁷District Hospital in Chrzanow, Topolowa 16, 32-500 Chrzanow, Poland
⁸Murcki Hospital Sp. z o.o., Sokołowskiego 2, 40-749 Katowice, Poland
⁹Jędrzej Śniadecki Specialist Hospital in Nowy Sącz ul. Młyńska 10, 33 – 300 Nowy Sącz, Poland
¹⁰Jędrzej Śniadecki Specialist Hospital in Nowy Sącz, Młyńska 10, 33 – 300 Nowy Sącz, Poland

^♦Corresponding author
Aleksandra Paprocka, Jan Mikulicz-Radecki University Clinical Hospital, Borowska 213, 50-556 Wroclaw, Poland

ABSTRACT

Lycopene is a chemical compound that occurs in red fruits and vegetables, such as tomatoes. Lycopene has potent antioxidant and anti-inflammatory properties. Processes that influence the development of civilization diseases. The aim of the study is to explore the impact of Lycopene in the prevention and treatment of civilization diseases such as hypertension, atherosclerosis, metabolic diseases, and various cancers, in the latest research. Moreover, it will indicate directions for future research that will allow for a better understanding of the role of this compound. In conclusion, a diet rich in lycopene demonstrates potential in preventing and mitigating the severity of various civilization diseases. Therefore, the article describes a current review of research and literature in this area of knowledge. The studies presented in this article show the potential of prevention and treatment of cardiovascular, metabolic diseases, and various cancers. However, long-term studies on larger groups of subjects are needed to fully understand lycopene's potential.

Keywords: lycopene, oxidative stress, cardiovascular diseases, cancer, civilization diseases

Medical Science, 2025, 29, e72ms3585

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DOI: https://doi.org/10.54905/disssi.v29i158.e72ms3585

Published: 27 May 2025