Volume 28, Issue 150, August 2024

Diffuse large B-cell lymphoma (DLBCL) accompanied by a pathologically enlarged pack of lymph nodes: A review

Anna Józefiak¹, Magdalena Szczepanik², Cezary Bochyński^3♦, Przemysław Hałasiński⁴, Dominika Kropidłowska⁵, Maciej Horbaczewski⁶, Kinga Piela⁷, Jolanta Mazurek⁸, Gabriela Mazurek⁹, Maria Myślicka¹⁰, Patryk Góralski¹¹, Klaudia Włodarczyk¹⁰

¹Department of Internal Diseases and Endocrinology, Gabriel Narutowicz Municipal Specialist Hospital in Cracow, Prądnicka 35-37, 31-202 Cracow, Poland
²Department of Pediatrics, District Hospital in Chrzanów, Topolowa 16, 32-500 Chrzanów, Poland
³Department of Internal Medicine, Railway Hospital. Włodzimierz Roefler, MD, PhD in Pruszków, Warsztatowa 1, 05-800 Pruszków, Poland
⁴Clinical Department of Gastroenterology, Metabolic, Internal Diseases and Dietetics, University Clinical Hospital in Poznań, 49 Przybyszewskiego, 60-355 Poznań, Poland
⁵Polish Red Cross Maritime Hospital in Gdynia, Powstania Styczniowego 1, 81-519 Gdynia, Poland
⁶Hospital Emergency Department, District Health Center Kartuzy, Floriana Ceynowy 7, 83-300 Kartuzy, Poland
⁷Hospital Emergency Department, University Clinical Hospital. Fryderyk Chopin in Rzeszów, Fryderyka Szopena 2, 35-055 Rzeszów, Poland
⁸Primary Health Care, Private Health Care Facility "ALMUS" Jacek Pieniazek, Białoboki 137, 37- 207 Gać, Poland
⁹Department of Cardiology and Internal Diseases, Gabriel Narutowicz Municipal Specialist Hospital in Cracow, Prądnicka 35-37, 31-202 Cracow, Poland
¹⁰Wroclaw Medical University, wyb. Ludwika Pasteura 1, 50-367 Wroclaw, Poland
¹¹University Clinical Center in Gdańsk, Dębinki 7, 80-952 Gdańsk, Poland

^♦Corresponding Author
Department of Internal Medicine, Railway Hospital. Włodzimierz Roefler, MD, PhD in Pruszków, Warsztatowa 1, 05-800 Pruszków, Poland

ABSTRACT

Introduction: Diffuse large B-cell lymphoma (DLBCL) is a relatively common lymphoma with an aggressive course. A complete cure is possible for this type of lymphoma. The etiology of this cancer is unknown, but a number of factors, including environmental factors, contribute to the onset of this disease. The aim: The purpose of this article is to present diffuse large B-cell lymphoma as a curable disease if detected and treated early enough. Case report: The described case is a 70-year-old patient who came to the doctor with a neck tumor. After taking an interview, taking a history and physical examination, and making a diagnosis, the patient was diagnosed with Diffuse large B-cell lymphoma. Results: DLBCL is the most common lymphoma type in adults, characterized by highly aggressive and dynamic development. Diffuse large B-cell lymphoma most often occurs in older people, around 70 years old. The diagnosis of DLBCL is based on histopathological examination of a sample taken during surgery, i.e., the cancerous lymph node. In this type of lymphoma, complete recovery is possible with early diagnosis and treatment. Conclusions: Due to the aggressive development of Diffuse large B-cell lymphoma, only rapid diagnosis and treatment can ensure tumor regression. Diagnosis of cancer is based on histopathological examination, while treatment is based on surgery and subsequent postoperative chemotherapy.

Keywords: Neck tumor, lymphoma, DLBCL, diffuse large B-cell lymphoma

Medical Science, 2024, 28, e90ms3404

PDF

DOI: https://doi.org/10.54905/disssi.v28i150.e90ms3404

Published: 07 August 2024