Introduction: Constipation is prevalent worldwide (6.6%-10.1%). Its association
with diabetes mellitus (DM) is clear; it affects the quality of life, and diabetic
complications could potentially worsen. Although recognized, data on the
prevalence of constipation in diabetic populations is lacking. Especially
regionally, is scarce. This study aims to fill this gap and provide insights for
targeted interventions to enhance management. Material and Methods: The study
employed a cross-sectional design. Participants were recruited from diverse
healthcare establishments across urban and rural regions. Data collection
involved two parts of questionnaires: One structured questionnaire, and the
other gastrointestinal Quality of Life Index (GIQLI), analyzed using the SPSS
program. Results: This study included 289 diabetic patients in Saudi Arabia’s
Qassim region. Constipation was prevalent in 30.4% of participants. Type 2
diabetes was more prevalent (93.8%), with an average duration of 18.81 years and
a mean HbA1c level of 7.47%. Constipated patients reported significantly lower
gastrointestinal Quality of Life Index (GIQLI) scores (65.8) compared to nonconstipated
individuals (87.2). Multiple logistic regression analysis identified
advanced age as slightly decreasing the risk of constipation at, the same time,
longer diabetes duration, presence of coronary heart disease, insulin therapy, and
lower GIQLI scores were significant independent risk factors for constipation
symptoms. Conclusion: Constipation symptoms were prevalent in nearly onethird
of diabetic patients. Independent risk factors, including advanced age,
longer diabetes duration, presence of coronary heart disease, insulin therapy, and
lower gastrointestinal quality of life scores, emphasize the necessity for targeted
strategies to manage constipation in diabetic populations.
Keywords: Constipation prevalence, diabetes mellitus, gastrointestinal quality of
life, risk factors
