Volume 28, Issue 149, July 2024

Effectiveness of Bilevel positive airway pressure ventilation for acute respiratory failure patients: A systematic review

Mohammed Ayed Algamdi, Mohammed Saleh Almulhim, Abdullah Sultan Alangari, Saud Abdullah Alsalem, Abdulaziz Fahad Alkharji, Khalid Mefleh Alrasheedi, Abdulkarim Farhan Alanazi, Wael Mohammed Alqahtani, Fahad Mohammed Alsahli, Khalid Rikaa Almatrafi

Respiratory Therapist, National guard hospital, Riyadh, Saudi Arabia

ABSTRACT

Background: It's uncertain if BiPAP helps people with acute respiratory failure. This research aims to determine if BiPAP is effective for people with acute respiratory failure. Method: The PRISMA guidelines were adhered to in this systematic study. Cochrane, MEDLINE, EMBASE, CINAHL for papers released between 1997 and 2024. Only randomized controlled studies comparing the effectiveness of continuous positive airway pressure with oxygen therapy, NIVVAVA, or BiPAP ventilation in patients with ARF were included. Mortality, length of hospital stay, and ETI rates were the main outcomes of interest that were compared between the two groups in order to evaluate efficacy. Result: Eight studies totaling 524 people were enrolled in the review; 5 of the studies utilized CPAP as the control group, one used NIV-VAVA and two of the studies used oxygen. All of the articles included are randomized controlled trials that were carried out in the emergency setting or intensive care unit. Except for two studies where the underlying cause was solid tumor end stage and COPD, the underlying cause of abrupt respiratory failure in all included trials was cardiopulmonary edema. In most of the examined publications, the main outcomes were, mortality, endotracheal intubation and length of hospital stay. Conclusion: We conclude from our systematic investigation that NIV use in ARF parents reduce the risk of complications and mortality in cardiopulmonary edema patients, and that BiPAP beneficial as CPAP.

Keywords: Acute respiratory failure, endotracheal intubation, mortality, noninvasive ventilation, Bi-level positive airway pressure

Medical Science, 2024, 28, e78ms3394

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DOI: https://doi.org/10.54905/disssi.v28i149.e78ms3394

Published: 21 July 2024