This study aimed to evaluate prevalence, determinants and associated quality of life impairment due to migraine headache among the population of Jeddah city, Saudi Arabia. A cross sectional study was conducted using the convenient sampling technique via Online-Google form questionnaire. It provided information on: Personal and sociodemographic characteristics, morbid history, clinical aspects of migraine headache and quality of life. Logistic regression and factor analyses were used. Of all the participants, 69% had headache; however, migraine was diagnosed among 38.6% (59/153) of the participants. The subjects with positive family history of migraine were 4.6 times more likely to have migraine compared to those without (OR: 4.564; 95% CI: 1.811, 11.503, p < 0.001). The participants with Migraine were 9.1 times more likely to use OCT drugs (particularly NSAIDs) compared to those without (OR: 9.098; 95% CI: 3.107, 26. 636, 503, p < 0.000). Factor analysis showed that Migraine was associated with restriction of ability to concentrate on work and home activities (weight = 0.206), with feeling angry because of headache (weight = 0.207) and with feeling tired to do work or home activities (weight = 0.203). Migraine headache, is a common health problem that affects the quality of life of the affected population of Jeddah City Saudi Arabia.
Keywords: Migraine headaches, Quality of life, Saudi Arabia