In developing nations, tuberculosis (TB) continues to be a serious health issue, with India bearing the majority of the burden. It comes in a wide variety of presentations and complications. Its propensity for thrombogenesis is a worrying consequence that significantly increases morbidity. Numerous mechanisms of tuberculosis can cause a hypercoagulable condition and thromboembolic consequences. We report a case of a 37-year-old male who had inferior vena cava thrombosis with multidrug-resistant pulmonary tuberculosis (MDR-TB). It was discovered that early diagnosis, anti-TB medication start-up and suitable anticoagulant therapy could save lives. The use of an IVC filter as a treatment in this instance reduced the disease's total morbidity and mortality. The co-treatment with the longer oral bedaquiline containing MDR regimen and anticoagulant therapy is being followed closely in this case and will be a useful tool in the future for further management of such patients.
Keywords: Inferior Vena Cava Thrombosis, Tuberculosis, Multi-drug Resistant Tuberculosis, MDR-TB