Volume 27, Issue 134, April 2023

Giant dumbbell shaped malignant peripheral nerve sheath tumour arising from sciatic nerve: A case report

Rahul Rajendran¹, Bhushan Jajoo^2♦, Raju Shinde³, Tejashree Telkhade⁴, Sameeksha Dubey⁵

¹Junior Resident, Department of General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India
²Assistant Professor, Department of Surgical Oncology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India
³Professor, Department of General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India
⁴Assistant Professor, Department of Radio Oncology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India
⁵Assistant Professor, Department of Medical Oncology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India

^♦Corresponding author
Assistant Professor, Department of Surgical Oncology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India

ABSTRACT

Malignant peripheral nerve sheath tumours in the sciatic nerve are sporadic and are often misdiagnosed. We herein report a case of a 22-year-old woman presenting with low back pain radiating to the right lower limb and right lower limb weakness. CT and MRI scan showed a large complex solid cystic lesion arising from S1 and S2 nerve roots extending from the right presacral space and traversing through the obturator foramina and emerging in the right gluteal region. Surgical resection with a bi-modal (Trans abdominal and gluteal) approach resulted in complete excision of the mass with an appreciable margin. The histopathological report showed a malignant peripheral nerve sheath tumour. Post tumour board discussion patient underwent adjuvant radiation. The patient has been under regular follow-up for six months and is disease-free.

Keywords: Malignant peripheral nerve sheath tumour (MPNST), dumbbell shaped, sciatic nerve, computed tomography (CT), magnetic resonance imaging (MRI), radiation therapy.

Medical Science, 2023, 27, e176ms2810

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DOI: https://doi.org/10.54905/disssi/v27i134/e176ms2810

Published: 03 April 2023