Volume 27, Issue 133, March 2023

Assessment of QTc interval changes in patients undergoing spinal anesthesia for elective surgery

Mohsen Sahebanmaleki¹, Mahdi Basirimoghadam², Reza Ghasemi³, Mahdi Pirzadeh Aval Baghciahi^4♦, Sepideh Karkon Shayan⁵

¹Assistant Professor of Anesthesiology, MD, FCCM, Department of Anesthesia, Clinical Research Developmental Unit Bohlool Hospital, Gonabad University of Medical Science, Gonabad, Iran
²Nursing Care Research Center, Iran university of Medical Sciences, Tehran, Iran
³Associate Professor of Cardiology, Torbat-e Heydarieh University of Medical Sciences, Torbat-e Heydarieh, Iran
⁴MSc Student in Nursing Education, Gonabad University of Medical Sciences, Gonabad, Iran
⁵Student Research Committee, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran

^♦Corresponding author
MSc Student in Nursing Education, Gonabad University of Medical Sciences, Gonabad, Iran

ABSTRACT

Background and Aim: A prolonged QT interval is one of the causes of sudden death and the occurrence of arrhythmias. It is needed to revision more the increasing frequency of spinal anesthesia and unidentified causes of some of its complications, such as sudden and preventable death. This study aimed at examining the QTc interval changes in patients undergoing spinal anesthesia for elective surgery. Materials and Methods: This is an analytical study conducted from March 2020 till Feb 2022. We studied QTc interval changes before, during and after the spinal anesthesia. 177 patients aged 20-60 years selected for spinal anesthesia. The electrocardiogram (ECG) performed three periods before and 10 and 150 minutes after anesthesia. Data collected and analyzed via SPSS ver. 14.5. The significance level was P-value<0.05. Results: The average QT interval before operation, during operation and after operation was respectively (365.35 ± 30.32), (374.36 ± 28.99) (377.74 ± 30.52) and this difference is statistically significant. It was significant (P=0.01). The average QTc interval before operation, during operation and after operation was respectively (407.88±29.11) (408.13±26.22) (408.13±26.22) which was statistically significant (p = 0.03). Conclusion: Marcaine increased the QTc interval during spinal anesthesia, which was statistically significant. But spinal anesthesia had no significant effect on PR interval.

Keywords: Spinal Anesthesia, QTc interval, sudden death

Medical Science, 2023, 27, e161ms2708

PDF

DOI: https://doi.org/10.54905/disssi/v27i133/e161ms2708

Published: 27 March 2023