Volume 27, Issue 133, March 2023

A rare case of VACTERL association in new born

Rasagnya M Reddy^1♦, Bhavana B Lakhkar², Mahaveer S Lakra¹, Sagar Karotkar¹, Kiran Khedkar³, Amar Taksande¹, Revat J Meshram¹, Mayur B Wanjari⁴

¹Department of Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India
²Department of Pediatrics and Neonatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, wardha, Maharashtra, India
³Department of Pediatric Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India
⁴Research Scientist, Department of Research and Development, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India

^♦Corresponding author
Department of Pediatrics, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India

ABSTRACT

VACTERL Association is complex, non-random sporadic association of various birth defects. It includes vertebral, anal anomalies, cardiovascular, tracheoesophageal, renal anomalies, radial anomalies and limb abnormalities. It is first described in 1970s. Full spectrum association is a very rare entity. VACTERL is considered to be present if any three of the above-mentioned abnormalities are present. Along with these features, patients might present with other external anomalies like lung lobation defects, external ear anomalies etc. However, the full spectrum of VACTERL association is very rare diagnosis mainly by clinical approach. Multidisciplinary approach and treatment of surgically correctable anomalies provide a better outcome for this association in new born period. Tracheoesophageal fistula is associated in more than 70 percent of the cases. Limb defects are also present in 70 percent of the cases. Anal atresia is present in 55 percent of the cases. VACTERL Shows phenotypic overlap with various conditions like Goldenhar syndrome, Fanconi anaemia, CHARGE syndrome etc. Here in we are reporting a case of VACTERL with presence of cardiovascular abnormality, Tracheoesophageal fistula and limb abnormalities.

Keywords: Cardiovascular abnormality, Tracheoesophageal fistula, lung lobation

Medical Science, 2023, 27, e147ms2837

PDF

DOI: https://doi.org/10.54905/disssi/v27i133/e147ms2837

Published: 15 March 2023