In clinical practice, treating teeth with an open apex necessitates caution and diligence. In such circumstances, the grade of apical
obturation has a direct bearing on the prognosis of endodontic treatment. Previously, a calcified barrier using calcium hydroxide
treatment was advised as a therapy option for these patients; however, due to the method's numerous drawbacks, the current
management approach advises apexogenesis via regenerative endodontic therapy. This report describes a case of “regenerative
endodontic treatment” performed in “immature permanent tooth with pulp necrosis & apical periodontitis” as well as the
effectiveness of a PRF-based “regenerative protocol in non-vital young permanent tooth”. After 1 year follow up, the tooth was
clinically and radiographically asymptomatic and the healing of the apical area is visible.
Keywords: Apexogenesis; mineral trioxide aggregate; trauma