Radicular cysts are inflammatory lesions of the jaws in the tooth-bearing areas. These lesions more commonly involve the apex of
the associated tooth and have a well-defined radiolucency. Platelet rich fibrin is known as a healing biomaterial in oral surgical
defect with the new aspect of advanced healing of a bony defect. The present case is of large radicular cyst associated with root
canal treated maxillary permanent incisors in a 28-year-old boy and its surgical management with PRF augmentation as a healing
biomaterial in the bony defect. One-year follow-up showed satisfactory healing. Healing was relatively fast and enhanced by
placement of PRF without any post-operative complications.
Keywords: platelet rich fibrin, surgical management, radicular cyst