Volume 26, Issue 122, April 2022

Implication of chronic obstructive pulmonary disease on the severity and outcome of covid-19 in rural India; Is COPD the hidden culprit amongst the havoc: A cross sectional study

Dhruv Talwar¹, Sunil Kumar^2♦, Sourya Acharya², Deepak Talwar³, Shraddha Jain⁴, Neema Acharya⁵, Kamlesh Chaudhari⁵, Sparsh Madaan⁶, Vidyashree Hulkoti¹, Akhilesh Annadatha¹, Twinkle Pawar¹, Mansi Patel¹, Divit Shah¹

¹Post Graduate Resident, Department of Medicine, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India
²Professor, Department of Medicine, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India
³Chairman, Metro Centre for Respiratory Diseases, Noida, Uttar Pradesh, India
⁴Professor, Department of Otolaryngology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India
⁵Professor, Department of obstetrics and gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India
⁶Post Graduate Resident, Department of obstetrics and gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India

^♦Corresponding author
Professor, Department of Medicine, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi meghe, Wardha, Maharashtra, India

ABSTRACT

COVID-19 (Coronavirus infectious disease 2019) denotes an ever changing and varied disease which has crippled the health care systems throughout the world. There have been studies conducted across the globe to establish the important factors for severity and mortality associated with COVID-19. We tried to study the effect of chronic obstructive pulmonary disease (COPD) on the severity as well as outcome of COVID-19. Material and methods: A total of 180 patients with COVID-19 were enrolled in this study and were then screened for history of COPD. There were 49 patients with history of COPD and 131 patients with no history of COPD. Inflammatory markers and HRCT scores were assessed for all the patients and they were followed up to study the outcome. Result: COPD was significantly associated HRCT Score, inflammatory markers and outcome. The mean HRCT Score for patients with COPD was more in COPD group (15.39 ± 4.65) when compared with Non-COPD group (9.39 ± 3.98). Mortality was also significantly higher in patients with COPD (67.3%) when compared to the patients without COPD (3.3%). Conclusion: We conclude that COPD is an important factor which has to be considered while treating the patients of COVID-19 especially in the rural India where lockdown restrictions and lack of knowledge have provided hinderance in achieving optimal follow up as there is increased severity and mortality associated with it.

Keywords: Chronic obstructive pulmonary disease, COVID-19, Severtiy, Outcome, Mortality

Medical Science, 2022, 26, ms131e2150

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DOI: https://doi.org/10.54905/disssi/v26i122/ms131e2150

Published: 12 April 2022