The majorities of the population pay little attention to the health issues and accord little or no priority to medical checkup which
leads to the preference of Self-Medication practice. This study was conducted to determine the knowledge and practice of the
prevalence of self-medication among urban population in Makkah region. A descriptive cross-sectional study was conducted with a
target population of 1000 participants over the period of three months. The data was collected in the form of well designed specific
questionnaires related to self-medication along with other informations related to the bio-informatics of the individual, etc., both in
English and Arabic language. This cross-sectional survey study was conducted by blending both qualitative and quantitative
methods of data collection during an awareness campaign and through direct interview with the participant. The collected data
were analysed by the Microsoft Excel and SPSS. The values were presented as numbers (%). IBM SPSS, IBM Corp., Armonk, N.Y.,
USA, version 23 was utilized for analysis. Statistical comparisons were made by Pearson Chi- Square test. The data were significant
if P-values were < 0.05. The analysed results of the collected data suggested that the effort was needed in ensuring that the drive is
required to discourage the practice of the self-medication and encourage the visit to the medical practitioners to follow the proper
guidelines of the prescribed medications. It is necessary to study the factors associated with the uptake of medications among the
studied population and avoid the complications of self-medication.
Keywords: Makkah, Prevalence, Self-medication, Urban population