Volume 25, Issue 113, July 2021

Neonatal pneumothorax in association with APGAR score: A systematic review and meta-analysis

Nazim Faisal Hamed^1♦, Naif Mutkhan Alsharari², Ahmed Saeed Alshahrani³, Ghabban Ahmad Jamal R Ghabban³, Nawaf Oudah S Alhawiti³, Faris Faez R Alanazi³, Hamad Ibrahim H Albalawi³, Hashim Essam Salamah⁴, Bassim Khalid Alraddadi⁴, Abdalla Mohamed Bakr Ali⁵

¹Consultant of pediatrics, Maternal and child health care center, Tabuk, Saudi Arabia
²Consultant of pediatrics, Neonatology department, Maternal and child health care centre, Tabuk, Saudi Arabia
³Medical intern, Tabuk University, Tabuk, Saudi Arabia
⁴College of Medicine, King Abdualaziz University, KSA
⁵Faculty of Medicine, Sohag University, Egypt

^♦Corresponding author
Consultant of pediatrics, Maternal and child health care center, Tabuk, Saudi Arabia

ABSTRACT

Introduction: Pneumothorax (PTX) is a potentially fatal condition that primarily affects neonates. Premature babies are more likely to have underlying lung diseases, such as respiratory distress syndrome (RDS), which increases the risk of air leakage. Methodology: This was a systematic review and meta-analysis to estimate the association between neonatal PTX and Apgar score. A systematic electronic search was implemented through Google Scholar, PubMed, Web of Science, Science Direct, and EBSCO to include the eligible studies. Results: A total of 5 studies were included, with 357 patients (135 cases and 222 controls). The estimated association between the 5-minutes APGAR score and Neonatal PTX was [SMD=-0.91, (95% CI; -1.49, -0.33), P=0.002] and [SMD=-0.71,(95% CI; -1.01, -0.40), P=0.000] with the 1-minute APGAR score. Conclusion: We demonstrated a significant association between 1-minute and 5-minutes APGAR scores and neonatal PTX. The highest risk was found among neonates admitted to the ICU and those with persistent PTX.

Keywords: Neonatal pneumothorax; APGAR score; PTX; neonates

Medical Science, 2021, 25(113), 1731-1738

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