Volume 25, Issue 112, June 2021

Cytokine storm treated successfully with immunoglobulin therapy in a pregnant COVID-19 patient

Sparsh Madaan¹, Arpita Jaiswal^2♦, Sunil Kumar³, Deepika Dewani⁴, Dhruv Talwar⁵, Shivam Khanna⁵

¹Post Graduate Resident, Department of Obstetrics and Gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India
²Professor, Department of Obstetrics and Gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India
³Professor, Department of Medicine, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India
⁴Assitant Professor, Department of Obstetrics and Gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India
⁵Post Graduate Resident, Department of Medicine , Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India.

^♦Corresponding author
Professor, Department of Obstetrics and Gynaecology, Jawaharlal Nehru medical college, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India

ABSTRACT

Ever since its emergence Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV 2) has caused an enormous amount of morbidity and mortality. Pregnancy being a high risk state is also being affected by this lethal pandemic causing an increased risk of rising maternal mortality. The treatment strategies for managing COVID-19 in pregnant female remains limited with no definite treatment available. With the growing evidence of Lymphocytopenia in COVID-19 there has been a emergence of immunoglobulin (IVIg) as a relatively safe treatment option in immunodeficient states such as pregnancy. Though research remains limited in the aspect of immunoglobulin therapy in pregnancy a risk versus benefit ratio might allow use of immunoglobulin therapy. We present a case of COVID-19 associated cytokine storm with lymphocytopenia in a Pregnant female which was successfully treated with Immunoglobulin therapy.

Keywords: COVID-19, pregnancy, immunoglobulin therapy

Medical Science, 2021, 25(112), 1413-1416

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