Volume 25, Issue 107, January, 2021

Lack of correlation between vitamin D and alkaline phosphatase levels among Saudi population

Mohammed H Karrar Alsharif^1,2♦, Mohammed A. Noureddin³, Mohammed N M Alharbi⁴, Faisal S F Alharbi⁴, Abdullah T Alhaddad⁴, Salman S Bin Ofisan⁴, Nasser I Alshumaymiri⁴, Rasheed A Alhajri⁴, Abdulmajeed A Alhussain⁴

¹Department of Basic Medical Science, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia
²Department of Histology and Embryology, Medical Faculty, Ondokuz Mayis University, 55139 Atakum, Samsun, Turkey
³Department of Medicine, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia
⁴College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.

^♦Corresponding author
Department of Basic Medical Science, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia; Email: dr.anatomy83@yahoo.com

ABSTRACT

Objective: The present study evaluated the correlation between Vitamin D and Alkaline phosphatase levels among the Saudi population. Methods: Blood samples of patients with a complaint of pain in various body parts and other clinical symptoms of Vitamin D deficiency were tested for the levels of Vitamin D and ALP. The analyzes were carried out using SPSS version 20.0 software. Results: Vitamin D and ALP levels of 460 patients were analyzed. The mean levels of Vitamin-D and ALP were found to be 22.03±13.5 and 89.02±44.9. About 356 patients (77.4%) out of 460 had Vit-D deficiency, whereas 421 patients (91.5%) out of 460 had ALP at normal ranges. From the analysis based on the nationality, Saudi 223 patients out of 280 showed vitamin D deficiency and 257 patients out of 280 had normal ALP levels. No correlation between serum ALP and vitamin D levels was observed (r = 0.05, p = 0.2). Conclusion: serum alkaline phosphatase cannot be considered as a useful marker to represent the Vitamin D deficiency among the population.

Keywords: Vitamin D, Alkaline phosphatase, Saudi population

Medical Science, 2021, 25(107), 16-25

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