Volume 24, Issue 106, November - December, 2020

In situ study: Effect of a 10% Carbamide Peroxide whitening gel on enamel mineral density using NanoCT

Najlaa Y Qusti^1♦, Steven J Brooks², Paul A Brunton¹

¹The Department of Restorative Dentistry, School of Dentistry, University of Leeds, Worsley Building, Clarendon Way, LS2 9LU, Leeds, UK
²The Department of Oral Biology, School of Dentistry, University of Leeds, Worsley Building, Clarendon Way, LS2 9LU, Leeds, UK

^♦Corresponding author
Dr. Najlaa Qusti, The Department of Restorative Dentistry, Dental Specialist Centre, King Fahad Hospital, Ministry of Health, P.0.Box 50505, Jeddah 21533, Saudi Arabia. Email: najlaaqusti@gmail.com

ABSTRACT

Objective: Investigating effects of ten percentage from carbamide peroxide bleaching agent on possible demineralisation of enamel surface to include assessment of the mineral density of human enamel which measure through using X-ray NanoCT scanning technique. Methods: Sixty enamel slabs obtain from human molars. Four slabs from a single tooth were used for each intra-oral device (two slabs acting as controls and two slabs being subjected to bleaching). A total of 15 volunteers included in our investigation. The volunteers were advised to wear the intra-oral devices containing the slabs for a period 16 hours a day and the study duration of 14 days. Volunteers advise to wear intra-oral devices containing the slabs 16 hr a day for 14 days. Bleaching was carried out ex-vivo for 8 hr / day throughout used ten percentage from carbamide peroxide bleaching agent. Control slabs on appliance were treated with the control gel. The baseline mineral density of the enamel slabs was measured prior to the experiment using NanoCT scan and at end of the experiment post-bleaching procedure. This allowed changes in mineral density to be assessed in the bleached and unbleached slabs. Results: Daily bleaching production have no significantly effects on inner enamel while increasing mean mineral density at enamel surface by (6.8%), which might be refer to the peroxide incorporates in hydroxyapatite lattice and modifies mineral ratio. Significance: To simulated at-home, bleaching as possible, an in situ model selected. Bleaching with ten percentage of carbamide peroxide did not have detrimental effects on mineral density and increased mineral density.

Keywords: Dental bleaching, at-home bleaching, carbamide peroxide, enamel mineral density, in situ study, remineralisation, saliva.

Medical Science, 2020, 24(106), 4731-4745

PDF