Volume 24, Issue 105, September - October, 2020

Multiple Myeloma presenting as Hypercalcemic Crisis: A case report

Akhilesh Annadatha¹, Sourya Acharya², Samarth Shukla³, Amol Bhawane⁴, Anuj Varma⁵, Amol Andhale^1♦

¹Resident, Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
²Professor, Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
³Professor, Department of Pathology, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
⁴Asst. Prof, Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India
⁵Asso. Prof, Department of, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India

^♦Corresponding author
Resident, Department of Medicine, Jawaharlal Nehru Medical College, DattaMeghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha-442001, Maharashtra, India; Email: dramoljnmc@gmail.com

ABSTRACT

Multiple myeloma, a disease of the plasma cells, clinically presents as lytic bone lesions, hypercalcemia, renal failure, and secretion of either complete immunoglobulins (light and heavy chain) or incomplete immunoglobulins (light chain). The light chain secretion into urine is called as Bence Jones protein which is another characteristic of the disease. Hypercalcemic crisis is an acute condition which presents with Oliguria or Anuria and sometimes, Coma. The cause of hypercalcemic crisis is usually Primary Hypeparathyroidism. Hypercalcemia of malignancy is one of the rarer causes of the same. We present a case of Multiple Myeloma presenting as hypercalcemic crisis.

Keywords: Crisis, hyperparathyroidism, bence-jones, light chain, heavy chain

Medical Science, 2020, 24(105), 3148-3152

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