Introduction: Soft tissue opacities are relatively common cases seen in panoramic radiography. The purpose of this study was to
evaluate the frequency of these opacities in panoramic radiographs and their differential diagnosis, as well as their concurrent
incidence. Materials and Methods: In this descriptive-analytical study, panoramic radiographs of 384 patients attending Oral and
Maxillofacial Radiology Clinic of the Jundishapur School of Dentistry. Prevalence of types of radiopacity, their location and some
related factors such as age, gender and incidence were assessed. The data was then analyzed by SPSS software version 22 using Chisquare
and Mann-Whitney tests. Results: Frequency of soft tissue radiopacities was as follows: tonsilloliths 3.9%, carotid artery
arteriosclerosis calcification 21.8%, thyroid calcification 19%, antrolith 0.5%, pulp stone 9.9%, and stylohyoid ligament ossification
48%.The results of Chi-square test showed a significant relationship between the incidence of calcified atherosclerotic plaque and
stylohyoid ligament ossification (P = 0.001) as well as a significant relationship between thyroid calcification and stylohyoid ligament
ossification (P = 0.002). There was a significant difference between different age groups in terms of frequency of stylohyoid ligament
ossification, calcified atherosclerotic plaque, thyroid cartilage calcification (p<0.001). Conclusion: Due to panoramic radiography
prescribed by most dentists, it is important to consider soft tissue calcifications and ectopic calcifications. By observing these
calculations, the dentists can introduce the patients to relevant specialist for further follow-up examinations.
Keywords: soft tissue calcification, panoramic radiography