Volume 24, Issue 104, July - August, 2020

Outcomes of preterm infants 26 – 34 week’s gestation at a Vietnamese children hospital

Ngo Minh Xuan

Department of Pediatrics, Pham Ngoc Thach University of Medicine, Ho Chi Minh city, Vietnam; Email: xuanlien62@pnt.edu.vn

ABSTRACT

Objective: This study aims to explored the rates of complications related to preterm infants; characteristics of treatment, and the mortality of preterm infants 26 – 34 weeks gestation in Children hospital 2 (Vietnam). Methods: We retrospectively enrolled 215 preterm infants 26 – 34 weeks gestation entered Neonatology and Neonatal Resuscitation within 72 hours after birth. The complications related to preterm infants, characteristics of treatment, and the mortality was analyzed. Results: The incidence of complications related to preterm infants: respiratory distress syndrome (80%), chronic lung disease (9.3%), symptomatic patent ductus arteriosus (14.4%), late-onset sepsis (58.6%), late-onset pneumonia (40.5%), necrotizing enterocolitis (7%), retinopathy of prematurity treated by diode laser photocoagulation (1.4%), intraventricular/periventricular haemorrhage (5.6%). The incidence of intervention related to preterm: mechanical ventilation (44.2%), respiratory support with CPAP (90.7%), surfactant therapy (39.1%). Rates of mortality (10.2%), rates of mortality based on gestational age were 48.3%, 8.1%, and 1% at 26 – 28 weeks, 29 – 31 weeks, and 32 – 34 weeks, respectively. Over time from 50 – 80 days, mortality risk of preterm age group 29 – 31 weeks increased 10% while the age group 26 – 28 weeks increased by 50%. Conclusion: The high rate of preterm infants hospitalized with a diagnosis of respiratory distress syndrome. High rates of complications related to prematurity, such as late-onset sepsis, nosocomial pneumonia. High mortality rates and high mortality risk over time of preterm age group 26 – 28 weeks gestation.

Keywords: preterm infant, complications, mortality

Medical Science, 2020, 24(104), 2119-2125

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