Acute pulmonary embolism (PE) is a variant of venous thromboembolism which in some cases may be fatal if not treated promptly.
A high index of suspicion is required to diagnose PE in an appropriate clinical setting. Diagnostic approach usually starts with a
quantitative D-Dimer assay. CT pulmonary angiography usually confirms the diagnosis. Treatment modalities for acute pulmonary
embolism are ranges from systemic thrombolysis to surgical embolectomy. Now a days, catheter based revascularization procedures
are emerging as substitute of systemic thrombolysis/surgical embolectomy in intermediate and high risk cases. Ultrasound-assisted
catheter-directed thrombolysis (UACDT) is an emerging and evidence based modality in the treatment of pulmonary embolism. We
describe a case of a 40 year old hyperhomocysteinemic male with deep vein thrombosis and submasssive PE who presented with
acute Cor-Pulmonale and was successfully treated with catheter directed thrombolysis.
Keywords: PE, thrombolysis, embolectomy, surgical, cor-pulmonale