Volume 24, Issue 104, July - August, 2020

Histopathological profile of Saudi females with breast cancer at Albaha province, KSA: A retrospective study

Thamer H. Al-Ghamdi^1♦, Moataz M. Alhasan², Jiehan M. Hassan³, Hala A. Khalafalla⁴, Manal A. Khalaf⁵, Ihab Shafek Atta⁶

¹Consultant of visceral and general surgery, Department of surgery, Faculty of Medicine, Albaha University, Saudi Arabia
²Pathology Department- Faculty of Medicine, Albaha University, Saudi Arabia
³Pathology Department- Faculty of Medicine, Albaha University, Saudi Arabia, Faculty of Medicine, University of Khartoum, Sudan
⁴Pathology Department- Faculty of Medicine, Albaha University, Saudi Arabia, Faculty of Medicine, Omdurman Islamic University, Sudan
⁵Pathology Department, Faculty of Medicine, Albaha University, Saudi Arabia, Faculty of Medicine, Minia University, Egypt
⁶Pathology Department, Faculty of Medicine, Albaha University, Saudi Arabia, Faculty of Medicine, Al-Azhar University, Assuit, Egypt.

^♦Corresponding author
Consultant of visceral and general surgery, Department of surgery, Faculty of Medicine, Albaha University, Saudi Arabia; Email: tthaker@bu.edu.sa

ABSTRACT

Background: Breast cancer is the most common cancer worldwide and in King Saudi Arabia as well. This study aimed to determine the demographic characteristics and histopathological profile of females with breast cancer attending King Fahad hospital at Albaha-KSA. Materials and Methods: Retrospective descriptive study conducted in King Fahad Hospital at Albaha in the period between Jan 2014 through Dec 2018. We obtained data concerning the demographic and histopathological profile of 80 female patients with breast cancer during the study period. Results: 80 patients ranging in age from 28–86 years (mean 52 years) were included in the study with the peak incidence age in the 5th decade. In 54.2% of cases, the tumor was left-sided. Most of the tumors 62 cases; 77.5% were of Infiltrating ductal carcinoma, and mucinous is the least one (2 case; 2.5 %). Most of cases were of grade II 40 cases (50%). Ten ( 12.5%) cases had tumor size ≤2 cm and were considered as (pT1), 33 cases (41.3%) had tumor size of 2–5 cm and were categorized as (pT2), while 7 cases (8.75%) were categorized as pT3 tumor size ≥ 5 cm. Thirty cases (16.25%) of the involved lymph nodes were classified as pN1 (metastases in 1 to 3 regional lymph nodes), 5 cases (6.25%) were categorized as pN2 (metastases in 4 to 9 regional lymph nodes), while 7 cases (8.75%) were described as pN3 (metastases in 10 or more regional lymph nodes). Conclusion: Our study showed that the peak incidence age of breast cancer was the 5th decade of life while infiltrating ductal carcinoma (IDC) was the most common histological type.

Keywords: Breast Cancer, Histopathology, Albaha, KSA

Medical Science, 2020, 24(104), 2537-2543

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