Background: Effusion diagnosis usually presents a challenge to physicians, thus this study aimed to assess the effusion associated
comorbidities in a group of Saudi Patients. Methodology: In this study, 62 patients presented with effusions were retrospectively
investigated in King Khalid Hospital, Hail, Northern Saudi Arabia. The sample size representing one-year of a full coverage sample.
Results: The highest proportion of patients were found with Hypertension (HNT) followed by Diabetes Mellitus (DM), Cancer,
Ischemic Heart Disease (IHD), Chronic Kidney Disease (CKD), both Nephropathy& Hypothyroidism, both Hepatitis & Tuberculosis
(TB), Liver Cirrhosis, constituting 40/62(64.5%), 37/62(60%), 19/62(30.6%), 11/62(17.7%), 6/62(9.7%), 4/62(6.5%), 3/62(4.8%) and
2/62(3.2%), respectively. Conclusion: Effusions etiology can be linked to the most common comorbid diseases including
hypertension and type 2 diabetes mellitus, the highly prevalent comorbidities worldwide.
Keywords: Effusion, Exudate, transudate, hypertension, diabetes, cancer, comorbidities, Saudi Arabia