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Volume 20, Issue 79, May - June 2016

About the Cover

The health benefits of probiotic organisms are well documented. A large number of pharmaceutical formulations containing probiotic microorganisms are available worldwide. These formulations are generally composed of organisms specifically from the genera Lactobacillus and Bifidobacterium. To comply with the regulatory need for pharmaceutical preparations, the label claims of these types of microorganisms have to be maintained throughout the shelf life of the product. So the quality control specifications demand the development of different selective media for the enumeration of each type of microorganisms present in the formulations. The selective media for Lactobacillus acidophilus using ofloxacin (MRS) and Bifidobacterium animalis using mupirocin (MRS) were already reported. In this study the efficiency of MRS-Ofloxacin and MRS-Mupirocin media were evaluated for selective enumeration of Lactobacillus acidophilus ATCC 4356 and Bifidobacterium animalis ATCC 25527 respectively from their mixed population. Performance of the selective media was also statistically validated (Ref: Saha PK, Chowdhury S, Bhattacharjee D, Das S, Mukherjee S, Hazra A, Bhattacharyya BK. Evaluation of Selective Media for Enumeration of Lactobacillus acidophilus and Bifidobacterium animalis Present in Probiotic Formulations. Medical Science, 2016, 20(79), 104-109).

Table of Contents

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PERSPECTIVE

NMO-An Update

Saumya H Mittal, Salony Mittal, Tuhina Govil

Neuromyelitis Optica is an autoimmune condition whose diagnostic criteria are expanding. The clinical features of the disease are different from multiple sclerosis, a disease that was considered a larger entity that included neuromyelitis optica until the last decade. The diagnostic markers are ever expanding and so are the treatment options, many of which are under trial.

Medical Science, 2016, 20(79), 69-73

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CASE STUDY

A rare case of scalp space occupying lesion caused by cysticercosis without involvement of brain

Upadhyay PK, Gupta U, Singh R, Pandey S, MishraY, Pandey P

Scalp occupying lesion was being evaluated for infectious or tumorous lesion in middle age female which was removed under magnification and confirmed on histopathology as a lesion of cysticercosis.It is a rare presentationof scalp space occupying lesion of cysticercosis without brain involvement.

Medical Science, 2016, 20(79), 74-79

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ANALYSIS

Comparative Evaluation of Anti-Inflammatory & Anti-Tumorigenic efficacy of “The Walking Mango Tree" Bark extracts

Gautama Reddy KV, Sunil Kumar Manna, Meher Master Moos, Ravi Prakash N

Stem bark of mango tree (Mangifera indica) has been used in herbal medicine as anti-phlogistic, liver protective, kidney protective, hypotensive, diuretic, anti-cough and analgesic agent. However, the anti-cancer activity and the potential anti-cancer mechanisms of walking mango tree bark have not been elucidated.

Medical Science, 2016, 20(79), 80-90

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The study of incidence of multidrug resistant typhoid fever in children 1-12 years with special reference to in-vitro antibiotic sensitivity and resistance pattern

Dhale S, Waghela S, Phalke B, Sadhwani N

Enteric Fever commonly called as Typhoid Fever is caused by Salmonella enteric serovar typhi (S.typhi) a gram negative bacterium. Typhoid Fever is a distinctive acute multisystem febrile disease recognised as a major cause of morbidity and mortality. MDR enteric fever is defined as typhoid fever caused by S. typhi strains which are resistant to all first line drugs i.e; Chloramphenicol, Ampicillin and Cotrimoxazole.

Medical Science, 2016, 20(79), 91-103

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Evaluation of Selective Media for Enumeration of Lactobacillus acidophilus and Bifidobacterium animalis Present in Probiotic Formulations

Saha PK, Chowdhury S, Bhattacharjee D, Das S, Mukherjee S, Hazra A, Bhattacharyya BK

The health benefits of probiotic organisms are well documented. A large number of pharmaceutical formulations containing probiotic microorganisms are available worldwide. These formulations are generally composed of organisms specifically from the genera Lactobacillus and Bifidobacterium.

Medical Science, 2016, 20(79), 104-109

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LETTER

History taking in HIV infected - need to be changed

Deivam S, Prabhusaran N, Balasubramanian N

The epidemic of human immunodeficiency virus/ acquired immunodeficiency syndrome (HIV/AIDS) is in its third decade and has reached to alarming proportions worldwide (Kanekar, 2011). According to the Centers for Disease Control and Prevention, more than one million people are living with HIV (Ul Hassan and Rasool, 2013).

Medical Science, 2016, 20(79), 110-111

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RESEARCH

Evaluation of Invitro Antidiabetic Activity and Invivo Oral Glucose Tolerance Test of Rumex vesicarius

Nadiminti Satish Reddy, Vidyasabbani, Pravanthi B, Vishwanath Reddy P, Vijaya B, Ch.Venu

Rumex vesicarius is one of the famous medicinal plants used in the treatment of a large number of human ailments as mentioned in Ayurveda. The main objective of this work is to evaluate the invitro antidiabetic activity and invivo Oral Glucose Tolerance Test effects of ethanolic extract of Rumex vesicarius.

Medical Science, 2016, 20(79), 112-116

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