Alcohol-based hand sanitizers are essential for infection prevention, but in selected
clinical situations, they may also become a hidden source of highly concentrated
alcohol. This narrative review synthesizes evidence on intentional or concealed
ingestion of these products as a clinically relevant patient safety problem. PubMed
and Google Scholar were searched for case reports, poison center studies,
toxicological papers, reviews, and patient safety sources. Reference lists of key
publications were hand-searched, and an official NHS England patient safety
resource was also reviewed. Published reports describe ingestion in emergency
departments, hospital wards, psychiatric units, addiction treatment settings, and
postoperative care. The recurring pattern was the combination of patient
vulnerability, access to an alcohol-containing product, and delayed recognition of
sanitizer as a possible source of intoxication. Alcohol use disorder was the most
consistent risk factor, but psychiatric vulnerability, self-harm risk, delirium,
cognitive impairment, and older age were also relevant. Presentations ranged from
apparent alcohol intoxication to respiratory depression, recurrent altered
consciousness, acid-base abnormalities, cardiac arrest, and death. Persistent
intoxication, rising blood alcohol concentration, or unexplained laboratory
abnormalities may suggest concealed access to sanitizer. Methanol-contaminated
products represent a distinct toxicological and regulatory risk, associated with
severe metabolic acidosis, visual impairment, and death. Intentional or concealed
sanitizer ingestion appears to be infrequently reported, but it is clinically important
and potentially preventable. Prevention should be proportionate, risk-based, and
non-stigmatizing, preserving infection-control standards while reducing avoidable
harm in selected vulnerable patients.
Keywords: alcohol-based hand sanitizers; intentional ingestion; alcohol use
disorder; methanol poisoning; patient safety
