Volume 30, Issue 168, February 2026

Portal Vein Thrombosis a literature review of the clinical outcomes associated with different management strategies in patients with liver cirrhosis

Michał Dworak^1♦, Marta Kowalska¹, Tomasz Wiśniewski¹, Mateusz Matyja², Anna Mazur¹, Julia Brodziak¹, Katarzyna Fojcik¹, Wiktoria Ciszewska¹, Zofia Kosztyła-Czech¹

¹Medical University of Silesia, Poland
²Specialist Voivodeship Hospital of Saint Barbara No. 5 in Sosnowiec - Trauma Center, Poland

^♦Corresponding author
Michał Dworak, Medical University of Silesia, Poniatowskiego 15, 40-055 Katowice, Poland

ABSTRACT

Portal vein thrombosis (PVT) is a frequent complication in patients with liver cirrhosis, often leading to a deterioration in patients' clinical condition. The treatment of PVT relies on anticoagulation therapy. The main key of therapy is to achieve recanalization of the portal vein and reduce thrombus progression, leading to a reduced risk of portal hypertension-related complications. Numerous anticoagulant drugs, such as VKAs, DOACs, and LMWH, have been investigated regarding their effectiveness and safety profiles. This article presents a deep analysis of the effectiveness of various treatments for PVT in cirrhotic patients.

Keywords: Portal Vein Thrombosis, Cirrhosis, Anticoagulation, Recanalization, Transjugular Intrahepatic Portosystemic Shunt

Medical Science, 2026, 30, e24ms3769

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DOI: https://doi.org/10.54905/disssi.v30i168.e24ms3769

Published: 7 February 2026