Volume 29, Issue 156, February 2025

Pilomatrixoma in childhooddiagnosis and treatment. A review of literature

Aleksandra Anioła¹, Sandra Ważniewicz^1♦, Jagoda Saniuk²

¹University Clinical Hospital in Poznań, Przybyszewskiego 49, 60-355 Poznań, Poland
²Voivodeship Hospital in Poznań, Juraszów 7/19, 60-479 Poznań, Poland

^♦Corresponding Author
University Clinical Hospital in Poznań, Przybyszewskiego 49, 60-355 Poznań, Poland

ABSTRACT

Pilomatrixoma, a benign skin neoplasm growing from hair matrix cells, also known as calcifying epithelioma, is children's second most common benign skin tumor. Researchers reported two peaks in the incidence of the lesion, the first under the age of one and the second between the ages of 5 and 11. More often, the lesion appears in the female gender. Although the lesion is most often asymptomatic, proper diagnosis is essential. Histopathological examination confirms the diagnosis of pilomatrixoma. It is also crucial to exclude other skin lesions that may mimic pilomatrixoma, such as a dermoid or sebaceous cyst. The first choice of treatment is surgery; due to possible recurrence, it is necessary to excise the lesion with an adequate margin. The paper reviews the literature on pilomatrixoma in the pediatric population.

Keywords: Pilomatrixoma, children, Malherbe's calcifying epithelioma, betacatenin, nodular lesion

Medical Science, 2025, 29, e37ms3540

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DOI: https://doi.org/10.54905/disssi.v29i156.e37ms3540

Published: 18 February 2025