Our objective is to assess the knowledge, attitudes and practices of parents of children with sickle cell disease (SCD) towards vaso-occlusive crisis (VOC). Cross-sectional study, administered to patients following up in King Salman Armed Forces Hospital (KSAFH), Saudi Arabia. The study included 134 participants. Data analysis performed using Statistical Package for the Social Sciences. Regarding assessment of the participant’s knowledge only 0.9% had a low knowledge level, 54.3% had a moderate level and 44.7% had a high level. Evaluation of the participants' practices, 7% had a low level and 77.2% had a high-level practice. Participant’s attitudes level toward the VOC was good in 97.4% of participants, while 2.6% had a poor attitude. There was a good level of general knowledge among parents of SCD patients. However, their knowledge about the role of vaccines and hospital admission was inadequate. The adequate knowledge of the parents was transformed into good practices, where the highest percentage of the participants had high practices and attitude scores. We recommend establishing more education meetings with parents as this is the preferred source of information by the parents.
Keywords: Sickle, Cell, Knowledge, Attitudes, Practices