This research aims to compare the diagnostic accuracy of ultrasound
elastography to histology in evaluating prostate masses and assess its ability
to distinguish malignant from benign diseases. The research involved 60
individuals with elevated PSA values (> 4 ng/ml) and aberrant DRE results
were sent to our department. The trial lasted from August 2020 until February
2022. All patients gave informed consent and were aware of the potential
complications of the biopsy. All the patients had B mode. Transrectal
Ultrasonography, colour Doppler imaging, and transrectal real-time strain
elastography were performed. The final diagnosis was confirmed with
histopathological examination. The institutional ethics committee approved
the study, and all patients obtained informed consent. In our study, the strain
ratio has a sensitivity of 81.4%, a specificity of 83%, a positive predictive value
of 88.4%, a negative predictive value of 83.5%, and an accuracy of 91.5% when
a cut-off point of 5 is used to differentiate benign from malignant lesions.
According to our results, prostate Ultrasonography coupled with
elastography could be a valuable method for diagnosing malignant lesions
and helps in targeting biopsy.
Keywords: Prostatic cancer, Transrectal biopsy, Ultrasound elastography,
Strain ratio