Acute coronary syndrome (ACS) is one of the major life-threatening
conditions encountered on daily basis in the emergency department and one
of the leading causes of death in middle and old age with predominant
symptom as chest pain. ST elevated myocardial infarction (STEMI) can be
detected early by a vital assessment tool called Electrocardiogram (ECG). De
Winter T-wave ECG pattern is a rare incidence which is often unrecognized
by physicians, first described by Robert J De winter and colleagues in 2008 as
STEMI equivalent which signifies left anterior descending coronary artery
(LAD) occlusion. This case series highlights the use of thrombolytic agents in
absence of STEMI to prevent further myocardial damage and improve the
patient's outcome much before percutaneous coronary intervention (PCI).
Coronary revascularization on an emergency basis reestablishes coronary
blood flow and reduces mortality and hospital stay. The thrombolysis was
successful and the patient symptoms improved along with reversal of initial
ST-segment and T-wave changes. LAD was later confirmed by coronary
angiography and appropriate cardiac interventions were done.
Keywords: De winter sign, Inj. Reteplase, Thrombolysis, ACS (Acute
Coronary Syndrome), Chest pain