Volume 25, Issue 110, April, 2021

Assessment of control of bronchial asthma persistence and basic anti-inflammatory therapy volume control: School patients dynamic longitudinal monitoring results

Olena Koloskova, Natalia Shevchenko, Uliana Marusyk^♦

Department of Pediatrics and Children Infectious Diseases, Bukovinian State Medical University, Chernivtsi, Ukraine

^♦Corresponding author
Department of Pediatrics and Children Infectious Diseases, Bukovinian State Medical University, Chernivtsi, Ukraine; Email: marusyk.uliana@bsmu.edu.ua

ABSTRACT

The task was to study the characteristics of the control of symptoms of the disease at school age in order to improve the management of bronchial asthma in children. The study was conducted within the framework of the project of longitudinal monitoring of children's cohort formed by simple random sampling, which lasted 5 years. The control of the symptoms of the disease, the severity of the course and the response to the prescribed basic anti-inflammatory therapy were evaluated. The study covered 196 school children suffering from asthma in the non-attack period. The monitoring showed a significant 2.12-fold increase in the proportion of controlled asthma in the total cohort of patients, a statistically valid increase in the proportion of patients with low asthma control by 2.3-fold and a 1.9-fold decrease in the number of patients with partially controlled symptoms. The study showed that the proportion of patients with controlled persistent bronchial asthma during the observation period, according to the clinical-instrumental assessment scale, compared with the initial data, statistically reliably increased by 2.54 times. During the dynamic monitoring using the GINA questionnaire and the clinical-instrumental evaluation scale, a decrease in the proportion of uncontrolled asthma was revealed, contrary to the data of the AST test, which showed an increase in the number of such patients.

Keywords: Bronchial asthma, GINA, children, anti-inflammatory therapy, longitudinal monitoring

Medical Science, 2021, 25(110), 816-822

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