Volume 24, Issue 104, July - August, 2020

Trastuzumab induced cardiomyopathy with cerebellar stroke: Double Trouble

Sourav Chaturvedi^1♦, Amrutha Garikapati¹, Iftikar Ansari¹, Charan Bagga¹, Sunil Kumar²

¹Post graduate Resident, Department of medicine, Jawahar Lal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India
²Professor, Department of medicine, Jawahar Lal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India

^♦Corresponding author
Post graduate Resident, Department of medicine, Jawahar Lal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India Email: sunilkumarmed@gmail.com / Souravchaturvedi39@gmail.com

ABSTRACT

Trastuzumab is routinely used monoclonal antibody in the treatment of several cancers with high effectiveness, but its use is associated with cardiac toxicity which usually responds to cessation of the drug therapy. We present an unusual case in 40 year old female being treated for breast carcinoma with trastuzumab developed acute cardiac toxicity in form of cardiomyopathy without atrial fibrillation, who developed stroke.

Keywords: Trastuzumab, Toxicity, Cardiomyopathy, Cerebellar stroke

Medical Science, 2020, 24(104), 2424-2427

PDF