Volume 24, Issue 104, July - August, 2020

The relationship between vitamin D with breast cancer

Eman Taha Hamdi^1♦, Abdulsalam Tawfeeq Alsamarai², Ali Abbas Ali³

¹Department of Medical biochemistry, University of Samarra, Iraq
²Lecturer, Department of Medical biochemistry, University of Samarra, Iraq
³Department of Clinical oncology, Salahadden Oncology center, Iraq

^♦Corresponding author
Department of Medical biochemistry, University of Samarra, Iraq; Email: Hayder.adnan2010@gmail.com

ABSTRACT

Objective: Evaluate the association between vitamin D2 with breast cancer (BC). Methods: A case control study department of oncology, Salahaddin Hospital, during the period from July 2019 to January 2020. Data were obtained from 90 participants, 58 women with BC and 30 women as healthy control. The BC women were further subdivided into 20 women with chemotherapy (G1), 14 women received less than 6 doses of chemotherapy (G2), 15 women received more than 6 doses of chemotherapy (G3), 9 women received chemoradiation therapy (G4). Results: Vitamin D in all BC women was significantly lower compared to healthy control (25.36±5.53 ng/L), additionally it was lower in G1 (8.48±1.97 ng/L) compared to G4 (14.29±2.69 ng/L), G3 (9.52±2.59 ng/L) was lower compared to G4, no difference was observed between G1, G2 (10.35±2.83 ng/L), and G3. Conclusions: there is clear inverse association between vitamin D with breast cancer, especially in those with early BC compared to more advance cases.

Keywords: vitamin D, breast cancer, inverse relationship

Medical Science, 2020, 24(104), 2600-2603

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