Volume 24, Issue 101, January - February, 2020

About the Cover

Diabetes is a public health problem. Altered platelet morphology and function have been reported as a cause of microvascular and macrovascular complications in patients with diabetes mellitus. We conducted a cross-sectional study to compare MPV in type 2 diabetics (T2DM) and non-diabetics and study the relationship between MPV and glycemic control (HbA1C) in patients with T2DM in a rural backdrop of central India. Participants were distributed into 2 groups: the study group of patients with T2DM (n = 98) and control group with non-diabetics (n = 98). The study group were further sub-grouped as uncontrolled group (HbA1c > 7%) of diabetic patients and controlled group (HbA1c ≤ 7%) of diabetic patients.MPV was determined by cell counter. Study group and control group were then compared with regards to MPV and HbA1c. We found significantly higher MPV in diabetics as compared to non-diabetics. Also, we found a positive co-relation between MPV and HBA1c. One % increase in Hb1Ac led to an increase in 1.45 fl (1.37-1.52) of MPV. It is hypothesized that platelet hyperactivity in patients with T2DM is related with factors such as hyperglycemia, hyperlipidemia, insulin resistance, and antioxidant and inflammatory conditions.

Table of Contents

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ANALYSIS

Assessment of serum lipid profile in patients with thyroid disorders in a rural backdrop of central India

Anubhuti Dixit, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Abhay M Gaidhane, Quazi Syed Zahiruddin

Thyroid diseases are among the commonest endocrine disorders worldwide. Thyroid dysfunction can result in lipid abnormalities which increase the risk of endothelial dysfunction, hypertension and cardiovascular disease

Medical Science, 2020, 24(101), 1-11

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Assessment of mean platelet volume (MPV) in subjects with Type 2 Diabetes Mellitus (T2DM) in a rural backdrop of central India

Priyal Shrivastava, Mahalaqua Nazli Khatib, Shilpa Gaidhane, Dipti Shrivastava, Abhay M Gaidhane, Quazi Syed Zahiruddin

Diabetes is a public health problem. Altered platelet morphology and function have been reported as a cause of microvascular and macrovascular complications in patients with diabetes mellitus.

Medical Science, 2020, 24(101), 12-21

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CASE REPORT

Full mouth rehabilitation of a pediatric patient under general anesthesia-A case report

Shreyans Jain, Nilesh Rathi, Nilima Thosar, Sudhindra Baliga, Pooja Bhansali, Kalyani Rathi, Nikita Sharma

Dental caries is the one of the most common chronic childhood disease. In early childhood caries, there is early pulp involvement and gross destruction of the maxillary anterior teeth as well as posterior teeth

Medical Science, 2020, 24(101), 22-25

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RESEARCH

Cardiovascular sympathetic nervous system response to cold pressor test among patients with migraine

Mohamed Saad, Wael Gabr, Osama El-Azouni, Asmaa Farouk Enein

Autonomic nervous system (ANS) dysfunction is one of the main characteristics of migraine; however, the exact relationship between migraine and ANS is not clear

Medical Science, 2020, 24(101), 26-36

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Aortic Isthmus Color Doppler Indices in intrauterine Growth-Restricted Fetuses (A case control study)

Zahra Fardiazar, Masoumeh Favaedi, Asrin Babahajian, Simin Taghavi, Shamci Abbasalizadeh, Fatemeh Abbasalizadeh, Azadeh Azadi, Neda Shoari

Intrauterine growth restriction (IUGR) refers to a condition in which the fetus is smaller than expected owing to either intrinsic or environmental causes

Medical Science, 2020, 24(101), 37-46

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Risk predictor signs on digital panoramic radiographs associated with mandibular canal compression on CBCT: A singleblinded retrospective comparison study

Ahmed M Jan, Fatma F Badr, Daniah Alhazmi, Ghassan Darwish, Fatima M Jadu

Estimating the risk of inferior alveolar nerve (IAN) injury prior to mandibular third molar extraction is crucial. Whether this estimation should be done using panoramic radiographs or cone beam computed tomography (CBCT) is still controversial.

Medical Science, 2020, 24(101), 47-56

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ANALYSIS

Neonatal Outcomes of Rh Alloimmunization Pregnancy Treated with Intrauterine Transfusion

Shirin Niroomanesh, Salmeh Dadgar, Mahboobeh Shirazi, Fatemeh Rahimi Sharbaf, Fatemeh Golshahi

Fetal anemia is a major problem and cause of neonatal morbidities and mortalities. Maternal Rh allo-immunization has not been eliminated with subsequent erythroblastosis fetalis and hemolytic disease still occasionally occurring.

Medical Science, 2020, 24(101), 57-65

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RESEARCH

Diagnosis of splenomegaly with one-dimensional diameters in CT scan images in North-East of Iran and constructing a bestfit model for estimation of splenic volume

Masoud Pezeshki Rad, Maryam Salehi, Mohaddeseh Mohammadi, Fatemeh Soati

The purpose of present study was to evaluate the accuracy rate of diagnosis of splenomegaly with one-dimensional diameters in computed tomography (CT) scan images

Medical Science, 2020, 24(101), 66-74

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ANALYSIS

Comparison of BISAP (Bedside Index for Severity of Acute Pancreatitis) versus BALTHAZAR CTSI (Computed Tomography Severity Index) scoring in predicting the severity in acute pancreatitis

Surya Subramanian, Mohanapriya Thyagarajan, Manuneethimaran Thiyagarajan, Nitesh Navrathan, Balaji Singh Krishna

An often encountered surgical emergency is acute pancreatitis and poses a significant therapeutic challenge for the health care providers

Medical Science, 2020, 24(101), 75-82

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Prevalence, patterns and predictors of diabetes complications among patients with type 2 diabetes at Jazan Diabetic Centre, Saudi Arabia

Osama B Albasheer, Mubarack Sani, Al-baraa Abbas, Muaid Alfaifi, Mothana Najmi, Khalid Hakami, Mustafa Najmi, Yousef Abdali, Ayman Aysawi

The purpose of this study is to determine the prevalence, patterns and predictors of diabetes complications among patients with type 2 diabetes

Medical Science, 2020, 24(101), 83-89

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CASE REPORT

Lingual Lipoma: Rare case reported in Makkah, Kingdom of Saudi Arabia

Abrar Abdrabuh, Omar Halabi, Irfan Shaikh

Lipoma is common, asymptomatic, and slow- growing benign tumor of mature fat tissues, but it is very rare occurrence in the oral cavity.

Medical Science, 2020, 24(101), 90-93

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ANALYSIS

Comparison of blood constituents related to metabolic syndrome in different Mizajes (Temperaments)

Asghar Karbord, Marzieh-Beygom Siahpoosh, Mahdi Zahedpanah, Hadise Abbasi Niaraky, Zahra Babashaverdi, Mohadeseh Pournasrollah Zide, Mohammad Reza Sarookhani

According to Canon, illness could be without any established disease and without any manifested changes in measurable parameters

Medical Science, 2020, 24(101), 94-101

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Foldscope assisted microscopy for the examination of Soil Transmitted Helminths (STH)

Anil Tambekar, Nishant Burnase, Abhay Gaidhane, Punit Fulzele, Zahiruddin Quazi Syed

Conventional microscopic examination in the diagnosis of helminth infection is a widely accepted method worldwide (Jain et al., 2019).

Medical Science, 2020, 24(101), 102-106

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The effect of teaching negotiation styles to parents of female adolescents on parent-child relationship

Sahar Sobhani, Mohammad Reza Mansoorian, Ali Delshad, Yaser Rivandi

Adolescence is one of the important periods of life and transition from childhood to adulthood. Prevalence of many psychological problems such as depression, anxiety, and substance use disorder increases during adolescence.

Medical Science, 2020, 24(101), 107-112

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Assessment of Spinacia oleracea extract on the reversal of Edoxaban anticoagulation development in a rabbit model

Feras M. Almarshad

The disadvantage of Edoxaban use is the availability of definitive antidotes with many unfavorable effects.

Medical Science, 2020, 24(101), 113-117

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Evaluation of the effect of potassium abnormalities based on the Revised Trauma Score (RTS) in the multiple Trauma

Amin Saberinia, Saeed Safari, Mohammad Mehdi Forouzanfar, Anita Sabzghabaei, Sahar Mirbaha, Elham Gholami Kelishami

A trauma causes changes, which are known as the metabolic responses to an injury. In this regard, extracellular potassium level abnormalities can cause various clinical problems in trauma patients.

Medical Science, 2020, 24(101), 118-126

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A study of clinicopathological patterns of renal tumors among a Kurdish population in Kermanshah province, Western Iran

Babak Izadi, Somayeh Jalilian, Mazaher Ramezani, Masoud Sadeghi, Sedigheh Khazaei

Renal tumor is a serious public health problem which has been steadily increasing and varies in different regions. We purposed to check the clinicopathological features of renal tumors in Kermanshah (west of Iran).

Medical Science, 2020, 24(101), 127-134

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Evaluation of prevalence and severity of acute respiratory distress syndrome in hospitalized patients due to H1N1 outbreak in Kerman, Iran

Mehdi Ahmadi Nejad, Morteza Hashemian, Hoda Ganjalikhani, Maryam Ahmadipour

Influenza is an acute respiratory viral disease which affects the upper and lower respiratory tract. The main cause of hospitalization was involvement of lower respiratory tract in the form of primary viral pneumonia due to direct invasion of lung tissue by virus

Medical Science, 2020, 24(101), 135-142

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The effectiveness of a water sports program on the level of poly unsaturated fatty acids and the severity of the disease in children with Autism spectrum disorder

Mona Mostafa Abdou Sakoury, Mohammed Nader Shalaby, Ahmed Mohammed Elmaghraby, Israa Mohamed Omar, Mai Mostafa Abdelsadek Tahoun

The current research aims to identify the effectiveness of a recommended water sports program on the concentration levels of polyunsaturated fatty acids and the effectiveness of the program on the severity of autism

Medical Science, 2020, 24(101), 143-164

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RESEARCH

Seroprevalence and 16S rRNA gene sequence analysis of Brucella spp. among domestic ruminants in Northern Border, Saudi Arabia

Muaz Magzob Abdellatif, Yahia Hassan Ali Osman, Hussam Hassan Arafat, Ahmed Zein Elabdeen Mahmoud

Brucellosis is a worldwide bacterial zoonotic disease. In this study, seroprevalence of Brucella spp among domestic ruminants in Hail

Medical Science, 2020, 24(101), 165-173

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ANALYSIS

The effect of periodic exercise on the levels of vascular factor and functional index in patients with ischemic stroke

Kadkhodaei Khalafi M, Shakeri N, Ghazalian F, Shojaei M

By reducing or stopping blood flow, a part of the brain suffers from cerebral ischemia with neurological deficits. Angiogenesis can play a role in repairing a damaged brain tissue, as exercise has an inductive role in the prevention of vascular disease

Medical Science, 2020, 24(101), 174-182

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A comparison of the cytotoxic activity of cisplatin versus l-amino acid oxidase on squamous cell carcinoma cell line

Wael Y. Elias

This study used flowcytometry to compare the cytotoxic effect of cisplatin and L-amino acid oxidases (LAAOs) on the HEP-2 cell line 24- and 48-hours following treatment

Medical Science, 2020, 24(101), 183-189

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Factors related with breast self-examination in women: A cross-sectional study in Tehran Province, Iran

Seyed Fahim Irandoost, Sina Ahmadi, Homeira Sajjadi, Hassan Rafiey, Farhad Nosrati Nejad, Mohammad Ali Mohammadi Gharehghani, Neda Soleimanvandiazar, Sayede Mahboobeh Hosseini, Salah Eddin Karimi

Breast self-examination is one of the primitive methods to diagnosis of breast cancer as one of the health problems in the world. Breast self-examination as a low costs and simple method that can be performed

Medical Science, 2020, 24(101), 190-200

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RESEARCH

CDK1 and PLK1 are key regulator proteins in human Papilloma virus Type 16-Positive Cervical Cancer: A Network-Based Study

Seyedeh Zahra Mousavi, Vahdat Poortahmasebi, Talat Mokhtari-Azad, Shohreh Shahmahmoodi, Somayeh Jalilvand, Ezatollah Rafiei Alavi

Human papillomavirus (HPV) is the causative agent of cervical cancer. The purpose of present study was to provide a comprehensive protein-protein interaction (PPI) approach to identify the representative sub-networks for this cancer

Medical Science, 2020, 24(101), 201-214

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ANALYSIS

The effect of sharpness and contrast processing filter on the measurement accuracy of endodontic file length

Sanaz Sharifi Shooshtari, Mahshid Razavi, Razie Moarrefpour, Zohre Roozbahani

Precise determination of working length can be effective alternative for optimizing endodontic treatment. There are several methods for determining working length, including digital radiography

Medical Science, 2020, 24(101), 215-222

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RESEARCH

Growth kinetic comparison of Human Mesenchymal Stem Cells from Bone Marrow, Adipose Tissue and Decidua

Sepide Kazemi, Kazem Parivar, Nasim Hayati Roudbari, Parichehr Yaghmaei, Behnam Sadeghi

Mesenchymal stromal cells (MSCs) are undifferentiated cells with high proliferation potency. These cells can be characterized by their ability to self-renew and differentiate into specialized cell lineages

Medical Science, 2020, 24(101), 223-234

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ANALYSIS

Prevalence of flat foot in Saudi Arabian primary school children in relation to age, gender, height and obesity: A cross-sectional study

Abdullah M. Al-Shenqiti, Reda S Eweda, Hatem A. Emara, Osama Ahmed Khaled, Sameh R. Ibrahim, Mostafa S. Ahmed, Mona Ibrahim Mohamed, Tarek Mohamed El-gohary

Flatfoot is a common problem in school age children, many factors may predispose to the development of flatfoot such as overweight, hypo kinesis, or hereditary factors

Medical Science, 2020, 24(101), 235-242

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Impact of Pender model training program on lifestyle of parents of children with Thalassemia Major

Maryam Shahraki, Mohammadreza Firouzkouhi, Abdolghani Abdollahimohammad, Mahin Naderifar

Improving the lifestyle and promoting health are fundamental needs for human beings. Parents of children with thalassemia need to enhance their lifestyles

Medical Science, 2020, 24(101), 243-248

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RESEARCH

Renoprotective influence of Teucrium polium leaf extract on Rats Intoxicated by Cyclophosphamide

Manal MS Mansoury

Teucrium polium leaves extract (TPLE) used as traditional herbal therapy for various diseases. Long term treated with Cyclophosphamide (CD) concomitant with development of renaltoxicity

Medical Science, 2020, 24(101), 249-258

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Evaluation of Lactobacillus reuteri probiotic Lozenge intake on Salivary Cariogenic Bacterial Counts in Preschool Children: A Randomized Clinical Trial

Eman S. Almabadi, Eman A. El Ashiry, Najlaa M. Alamoudi, Amani A. Al Tuwirqi, Rana M. Zeiton

The current study was conducted to assess whether intake of probiotic L. reuteri lozenges on a daily basis is beneficial to combat caries-associated salivary bacteria, namely Mutans streptococci and lactobacilli

Medical Science, 2020, 24(101), 259-269

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ANALYSIS

The effect of chronic diseases on the lifestyle of the elderly people in Baghdad city, Iraq: A cross-sectional study

Sarah Waleed Hashim, Rasha Zaki Shukur, Haider Mohammed Jaafer

The aim of the study is to assess the effect of chronic diseases on the lifestyle of elderly people. A cross sectional study with analytic element was conducted involving 210 participants of elderly people 60 years of age and above, sample from Baghdad

Medical Science, 2020, 24(101), 270-281

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The value of left ventricular strain in predicting adverse outcomes after coronary artery bypass surgery

Iman Rashid Al-Obaidi, Walla Lauy Al Falluji, Hayder Adnan Fawzi, Wisam Salih Al-Obaidi, Ali Abdul-Amer Al-Moswee, Azhar Jihad Salman, Ahmed Sameer Alnuaimi

Assess the validity of global LV strain and strain rate (SR) to conventional echo parameters and N-Terminal proBNP (Brain Natriuretic peptide) in patients with CAD (coronary artery disease).

Medical Science, 2020, 24(101), 282-289

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RESEARCH

Metallothionein induction ameliorates cisplatin-induced hepatotoxicity: Molecular and Cellular Study

Shareefa A. Al Ghamdi, Ahd Y. Al Zamil, Maryam A. Al Ghamdi, Huda F. Al Shaibi, Fahad A.Al-Abbasi

Cisplatin is effective as a chemotherapy treatment, but its toxicity is one of the undesirable effects that limit cisplatin use in cancer patients.

Medical Science, 2020, 24(101), 290-300

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ANALYSIS

Detecting probable coronary insufficiency in asymptomatic hypercholesterolemic individuals by treadmill exercise electrocardiography

Raed Dheyaa Jaafar

Assessment of the possible presence of silent coronary insufficiency (SMI) in hypercholesterolemic individuals who are not complaining of documented atherosclerotic disorders

Medical Science, 2020, 24(101), 301-307

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Explaining reduced consumption of sweet from the perspective of mothers: A qualitative content analysis

Seyed Saeed Mazloomy Mahmoodabad, Fatemeh Jowzi, Aliakbar Vaezi, Hassan Mozaffari-Khosravi, Hosein Fallahzade

Several studies have shown that there is a significant statistical relationship between sugar consumption and the prevalence of diabetes.

Medical Science, 2020, 24(101), 308-316

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RESEARCH

Comparison of Kyphoplasty and Vertebroplasty to increasing the height of vertebral body in Osteoporotic VBF

Sahar Farzi, Hesam Abdolhoseinpour, Reza Akhavan Sigari

Introduction & Objective: Vertebroplasty and kyphoplasty are low invasive procedures to strengthen the osteoporotic vertebrae

Medical Science, 2020, 24(101), 317-326

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ANALYSIS

Prevalence of Seizure between Chronic Renal Failure Patients in hemodialysis center, King Abdulaziz University Hospital

Aysha A. Alshareef, Manal M. Alzahrani, Ahd F. Almarzouki, Khalid S. Alhunaiti, Mawadda A. Bayazeed, Shaza A. Alshahrani

Background and aim: Chronic kidney disease (CKD) is a common co-morbid and a reason behind patient hospitalization in the medical practice in Saudi Arabia

Medical Science, 2020, 24(101), 327-334

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RESEARCH

Seroprevalence of HBV and HCV among chronic liver disease patients

Prasant HA, Lalithambigai J, Prabhusaran N, Uma A

Background: Serological investigation and exact identification procedures are very important to impart the hepatitis infection control in the initial stage itself in order to avoid the major complications including chronic liver damage to successive organ failure

Medical Science, 2020, 24(101), 335-342

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Investigation of the effect of L-Carnitine on Mouse Ovarian Transplantation

Fatemeh Shahi Sadrabadi, Hussein Eimani, Kazem Parivar, Abdolhussein Shahverdi

Introduction: L-carnitine (LC) has yielded relevant results on ischaemic/ reperfusion (I/R) injuries in organs such as the intestine, liver, kidney, brain and heart, because of its antioxidant activity

Medical Science, 2020, 24(101), 343-350

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ANALYSIS

Dietary habits, eating practices and lifestyle pattern as predictors of increased waist circumference amongst University of Umm Al-Qura female students: A cross-sectional study (Obesity Associated Risk Factors)

Mazen M. Ghaith, Mohammed O. Ibrahim

Objective: Waist circumference (WC) is considered one of the best indicators for assessing abdominal obesity

Medical Science, 2020, 24(101), 351-359

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Primary postpartum hemorrhage: Incidence, risk factors, and outcomes in Al Sader teaching hospital

Kawakeb N Abdulla, Anwar Ahmed Mohammed, Hayder Adnan Fawzi

Objective: evaluate the incidence, risk factors, causes and outcomes of primary postpartum hemorrhage (PPH).

Medical Science, 2020, 24(101), 360-364

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Health related quality of life for geriatrics patients with common chronic diseases among National Guard Population, Jeddah, Saudi Arabia 2018-2019

Ahmed Ghazi Kamal, Badr A Aljasir, Hani S Al-mugati, Amina Bargawi, Hassan Bin Usman

Background: Chronic diseases can have a profound impact on the health and quality of life of elder, not to mention the financial burden that is often associated with long-term illness

Medical Science, 2020, 24(101), 365-375

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SURVEY

GATS core survey in a highly urbanized city

Jo Ann Andoy Galvan, Donnabel Tubera-Panes

The Core Adult Tobacco Survey (CATS) was developed from the Philippine Global Adult Tobacco Survey (GATS), which was a nationally representative household survey

Medical Science, 2020, 24(101), 376-385

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ANALYSIS

Effect of prophylactic intravenous Dexamethasone and Lidocaine on cough and sore throat after extubation in elective laminectomy surgery

Nazli Karami, Alireza Mahoori, Hamid Aghaei

Context: In spite of advancement in anesthesia and surgery, major operative procedures are accompanied by post-operative complications

Medical Science, 2020, 24(101), 386-392

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CASE REPORT

Acute organophosphate poisoning presenting with Cerebral Infarction: Association or Chance?

Srinivas Naik, Sunil Kumar, Vidya Hulkoti, Abhilash Mishra, Deep Hathi, Sreekarthik Pratapa

Common neurological complications of acute organophosphorous poisoning are coma, seizure, and muscle weakness with respiratory failure which occurs due to cholinergic crisis

Medical Science, 2020, 24(101), 393-396

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ANALYSIS

Attitude of parents and dentists about the restorative materials used in Pediatric Dentistry

Shirin Taravati, Targol Amini, Sahar Mohammadi

Background: This study aimed to assess the attitude of parents and dentists about the restorative materials used in pediatric dentistry.

Medical Science, 2020, 24(101), 397-406

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A study of the state of spiritual health and its relation to self-efficacy of nurses

Moradali Zareipour, Zhila Mohammad Rezaei, Farzaneh Jafari, Sheiyda Ghaderzadeh

Introduction and Objective: Spiritual health is an important and prominent aspect of a healthy life that transforms people's lives from material life to spiritual life

Medical Science, 2020, 24(101), 407-414

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Assessment of the cardiovascular response of Propranolol and lignocaine to endotracheal intubation

Isra Hamed Saeed, Hayder Adnan Fawzi

Objective: assessment of the effect of propranolol and lignocaine on the cardiovascular response to endotracheal intubation, compared to placebo (IV normal saline).

Medical Science, 2020, 24(101), 415-420

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Sleep quality among adults and older adult who lives in Residential Care Center - RCC

Aseel T. Suqati, Mohammed Basheikh, Siraj Wali, Salma Sit, Abdulrahman A. Alomari, Raed A. Alharbi, Murad A. Yasawy

Background/objectives: Sleep is an essential neurophysiological process; it integrates health of all parts of the body and restores physiological and psychological functions

Medical Science, 2020, 24(101), 421-428

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Satisfaction of patients who underwent a Septorhinoplasty with or without Allergic Rhinitis: A cross-sectional study at a tertiary hospital

Ahmed Almutairi, Mohammed Alghunaim, Abdulrahman A. Alsalim, Suliman Almasoud, Mohammed Alqabasani, Yazeed Alghonaim, Abdulrahman Alfayez

Background: Patients with a nasal obstruction frequently present at the clinic. The obstruction is managed by a septoplasty accompanied by an operation, a septorhinoplasty, to correct the nasal deformity

Medical Science, 2020, 24(101), 429-434

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