Volume 22, Issue 90, March – April, 2018

About the Cover

Dyspepsia which is a digestive syndrome with a prevalence of 50 % in some areas can be an important factor in Helicobacter pylori infection syndrome. This study was aimed to evaluate relative frequency of Helicobacter pylori infection and histological changes in dyspeptic patients presented to the Endoscopic unit of Shahid Rahimi and Shohadaye Ashayer hospitals in Khorramabad city, Iran. In this cross-sectional study, the population included all patients with dyspepsia referred to Endoscopic Unit of Shahid Rahimi and Shohadaye Ashayer hospitals in Khorramabad during the period of 2013-2015. After performing endoscopy, H. pylori diagnosis was done by biopsy method.In this study, 5213 patients with dyspepsia (including 49.2% male and 50.8% female) with the age range of 12 to 90 years (mean 17.36±48.24 years) were studied. From this population, 57.3 percent were infected with Helicobacter pylori (50.8 % of men and 49.2% women). Most positive cases were over 60 years old and the most histological changes were respectively chronic active gastritis (40.3%). Similar to other studies, the prevalence of Helicobacter pylori infection is average in the population; however, these rates might be reduced through increased awareness and health care

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ANALYSIS

Investigating prevalence of Helicobacter pylori and histological changes in patients with dyspepsia in Khorramabad City during 2013-2015

Mosayeb Morandini, Majid Firouzi, Shiva Shafizadeh, Soleiman Jaferian, Shahdokht Fathi Beiranvand, Farshad Roostae, Afshin Roostaei, Mohammad Javad Tarahi, Hamidreza Sherkatolabbasieh, Mahmoud Bahmani, Hamed Maleki, Asghar Alipour

Dyspepsia which is a digestive syndrome with a prevalence of 50 % in some areas can be an important factor in Helicobacter pylori infection syndrome. This study was aimed to evaluate relative frequency of Helicobacter pylori infection and histological changes in dyspeptic patients presented to the Endoscopic unit of Shahid Rahimi and Shohadaye Ashayer hospitals in Khorramabad city, Iran

Medical Science, 2018, 22(90), 111-117

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Evaluation of public health and its relationship with burnout in nurses’ public and private hospitals of Khorramabad in 2016

Kourosh Saki, Maria Bahrami

The purpose of this study was to determine the relationship between general health and burnout in nurses of private and public hospitals in Khorramabad in 2015-2016. This correlational study was conducted on 350 nurses selected by stratified random sampling.

Medical Science, 2018, 22(90), 118-133

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RESEARCH

A randomized clinical trial; comparing levofloxacin based sequential and clarithromycin based sequential versus triple therapy for Helicobacter pylori eradication

Mosayeb Moradniani, Majid Firouzi, Soleiman Jaferian, Shiva Shafizadeh, Parastoo Baharvand, Hamed Maleki, Shahdokht Fathi Beiranvand, Nishtaman Ghaderi, Hamidreza Sherkatolabbasieh

Helicobacter pylori is a major cause of gastric diseases. Some studies in Iran showed that the resistance rate to clarithromycin was in the range of 5% to 45.2%. The present study aimed at evaluating the efficacy of a sequential therapy versus standard triple therapy in eradication of H.pylori infection.

Medical Science, 2018, 22(90), 134-139

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The impact of information therapy on stress in infertile young couples

Ali Maher, Tahere Behroozilak, Ahmad Hajebrahimi, Seied Mojtaba Hosseini

Infertility is a clinical term defined as the inability to conceive after at least 12 months of regular and unprotected intercourse. Acute and chronic stress has the ability to negatively affect infertility therapy, form a defective cycle and reduce the chance of succession even more.

Medical Science, 2018, 22(90), 140-147

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ANALYSIS

Investigation of the relationship between stress, burnout, job satisfaction of nurses working in oncology clinic

Semra Ayakdas RN, Elif Unsal Avdal, Burcu Arkan, Berna Nilgun Ozgursoy Uran, Barıs Onder Pamuk

This descriptive and correlational study aims to identify stress, burnout and job satisfaction of nurses working in oncology clinics. The sample of the study consist a total of 43 nurses working at oncology clinics at three University Hospital.

Medical Science, 2018, 22(90), 148-155

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Comparison of Milligan Morgan Hemorrhoidectomy and direct current electrotherapy for the treatment of Hemorrhoidal disease

Mehmet Kadir Bartın, Arzu Esen Tekeli, Esra Eker, Muzaffer Onder Oner

It is aimed to compare Milligan Morgan hemorrhoidectomy and direct current electrotherapy for the treatment of grade 2 and grade 3 internal hemorrhoids. Patients with symptomatic grade 2 or 3 internal hemorrhoids which is refractory to medical treatment were enrolled in this retrospective study.

Medical Science, 2018, 22(90), 156-161

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An analysis of the association between HbA1c levels of patients with type 2 diabetes and nutritional habits

Elif Unsal Avdal, Burcu Arkan, Nesil Gonen Atalay, Berna Nilgun Ozgursoy Uran, Baris Onder Pamuk, Nurcan Ozyazicioglu, Havva Gokdere Cinar

This study aims to identify the association between the nutritional habits of patients with type 2 diabetes and their HbA1c levels, and to determine the influences of nutritional habits on HbA1c levels. This descriptive, correlational, cross-sectional study was based on Type 2 diabetes and nutritional habits.

Medical Science, 2018, 22(90), 162-168

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RESEARCH

Association of haptoglobin phenotypes with susceptibility to migraine in an Iranian population: a preliminary study

Alireza Nakhaee, Alireza Khosravi, Jafar Poodineh, Masoud Sadeghi

Oxidative stress and nitric oxide (NO) are key factors in the pathogenesis of migraine. Haptoglobin-Hemoglobin (Hp-Hb) complex can reduce NO production and inhibit oxidative stress. Since the ability of different Hp phenotypes in the reduction of NO and oxidative stress are diverse; one influential factor in the pathogenesis of migraine may be Hp phenotypes.

Medical Science, 2018, 22(90), 169-175

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CASE REPORT

Induction of stable disease with combination of immunotherapy plus chemotherapy in metastatic Non-Small Cell Lung Cancer: A Case Report

Mehrdad Payandeh, Mehrnoush Aeinfar, Edris Sadeghi, Masoud Sadeghi

Programmed death ligand 1 (PD-L1) is part of an inhibitory checkpoint that helps protect against autoimmunity by acting as negative regulators of activated T cells.

Medical Science, 2018, 22(90), 176-180

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RESEARCH

Screening for metabolic syndrome in patients with bipolar disorder

Maryam Maddineshat, Hamid Reza Bayati, Atefe-Sadat Davudi, Sepideh Frozesh, Masoumeh Taherpour

Metabolic health threat to patients with bipolar disorder is of interest to many studies. This study aimed to screen metabolic syndrome in patients with bipolar disorder in a University Hospital Psychiatry Outpatient Clinic, Bojnurd, Iran.

Medical Science, 2018, 22(90), 181-187

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REVIEW

A comparison of the efficacy of twin block appliance compared with other functional appliances in class II malocclusion patients: A systematic review

Farshad Rahimi, Masoud Sadeghi, Hamid Reza Mozaffari

The main objective of therapy with twin block (TB) appliance is to induce supplementary lengthening of the mandible by stimulating increased growth at the condylar cartilage. Herein, the study evaluated the efficacy of TB appliance compared with other functional appliances in class II malocclusion patients.

Medical Science, 2018, 22(90), 188-202

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CASE REPORT

The Efficacy of Combination of Pembrolizumab plus Chemotherapy in Locally Advanced Squamous Cell Carcinoma of Mandible: A Case Report

Mehrdad Payandeh, Edris Sadeghi, Masoud Sadeghi, Mehrnoush Aeinfar

Pembrolizumab as a humanized monoclonal antibody blocks the interaction between programmed death ligand 1(PD-1) and its ligands that has been used for head and neck squamous cell carcinomas (HNSCCs).

Medical Science, 2018, 22(90), 203-208

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RESEARCH

Phenotypic and Molecular Characterization of Haemolysins in relation to Antibiotic Resistance Profile among Uropathogenic Escherichia coli (UPEC)

Sabitha Baby, Vimal Kumar Karnaker, Rishiyur Krishnaswamy Geetha

This study was conducted to detect the prevalence of haemolysis, its hly virulence genes and the antimicrobial resistance profile of Escherichia coli strains implicated in Urinary tract infections (UPEC) in Palakkad, India.

Medical Science, 2018, 22(90), 209-217

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ANALYSIS

Study of correlation between emotional intelligence and academic achievement among Iranian students in Zabol University of Medical Sciences, 2017

Mehdi Haghighi, Moin Khane Shir, Masoud Gholamzehi, Monireh Shamsai, Somayeh Bagheri

Academic life is one of the most important dimensions of life of individuals that has a great impact on other aspects of life. Among these, one of the basic problems of educational life of each country and educational system in each country, is the problem of academic failure and low level of academic performance of students and students in that country.

Medical Science, 2018, 22(90), 218-224

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The association between allergic rhinitis with migraine: A systematic review and meta-analysis study

Reza Fattahian, Masoud Sadeghi, Hamid Reza Mozaffari

Allergic rhinitis (AR) and migraine are two diseases with high rates in the population that can effect on quality of life. We aimed to assess the migraine frequency in patients with AR compared with controls in a meta-analysis study.

Medical Science, 2018, 22(90), 225-231

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RESEARCH

Role of Cymene in the attenuation of fatty liver and UCP2 gene expression

Hamedeh Bagheri, Parichehreh Yaghmaei, Mohamadhosein Modaresi, Azadeh Ebrahim-Habibi, Marjan Sabbaghian

Cymene is an organic aromatic and monoterpenic compound that has anti-inflammatory and antioxidant properties. This study investigates the effect of Cymene on biochemical and histological parameters and UCP2 gene expression in nonalcoholic steatosis model induced in male wistar rats.

Medical Science, 2018, 22(90), 232-242

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