Volume 20, Issue 80, July - August 2016

About the Cover

The pathological findings of brainstem nuclei in Alzheimer’s disease are reported, however, the clinical manifestation based on these affected brainstem nuclei has been uncertain. We describe some clinical manifestation possibly associated with brainstem pathological changes in Alzheimer’s disease. Most Parkinson’s disease patients show decreased 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy uptake. A decreased heart/mediastinum (H/M) ratio in MIBG scintigraphy has been attributed to Lewy body pathology in cardiac sympathetic nerves. Certain diseases such as Alzheimer’s disease, the Lewy body variant of Alzheimer’s disease, progressive supranuclear palsy (PSP), corticobasal degeneration, multiple system atrophy, and some cases of Parkinson’s disease can present with MIBG normal Parkinsonism. We aimed to elucidate the clinical and radiological features of MIBG-normal Parkinsonism or its subgroup. Sixty-one patients with Parkinsonism underwent MIBG myocardial scintigraphy, of which 22 showed normal MIBG. Of these patients, 5 demonstrated both magnetic resonance imaging (MRI) and single photon emission computed tomography (SPECT) findings consistent with Alzheimer’s disease.

Table of Contents

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CASE REPORT

Role of MRI in diagnosis of an unusual case of celiac disease presenting as hepatomegaly

Rajeshwari K, Mohammed Fazil A, Sapna Singh, Neeta Khurana, Anuradha S

Celiac disease is a gluten sensitive enteropathy usually presenting with gastrointestinal symptoms, but unusual presentations make the diagnosis of this disease sometimes challenging. Nodular regenerative hyperplasia (NRH) is a rare condition associated with connective tissue disorders, autoimmune diseases, haematological malignancy, drugs and is a cause of non cirrhotic portal hypertension.

Medical Science, 2016, 20(80), 117-122

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One Stage Excision of Intraspinal Tumour with Immediate Reconstruction of Spine by Laminoplasty – A Case Report

Upadhyay PK, Pandey P, Bora S, Pandey S, Gupta U, Singh R

Laminoplasty is a technique that indirectly achieves decompression of spinal cord and avoids the complications of fusion (Oyama, 1973). It was initially proposed by the Japanese as a treatment of ossified posterior longitudinal ligament in the cervical region. Its use has been expanded since then and is widely used in the thoracic and lumbar region (Lonstein, 1976).

Medical Science, 2016, 20(80), 123-131

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ANALYSIS

123I-metaiodobenzylguanidine myocardial scintigraphy-normal Parkinsonism with radiological features of Alzheimer’s disease - Parkinsonism variant of Alzheimer’s disease or Alzheimer’s disease with brainstem involvement?-

Naoki Kasahata, Fumihiko Tamamoto, Hiroyuki Kato

The pathological findings of brainstem nuclei in Alzheimer’s disease are reported, however, the clinical manifestation based on these affected brainstem nuclei has been uncertain. We describe some clinical manifestation possibly associated with brainstem pathological changes in Alzheimer’s disease.

Medical Science, 2016, 20(80), 132-141

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Rate of tinea pedis infection in a population of patients with diabetes mellitus

Ezejiofor OI, Ogualili PN, Nwaneli CU, Oguejiofor OC, Egwuatu CC, Anyabolu AE

Tinea pedis is a common superficial fungal infection caused by dermatophytes. It has a prevalence of about 10% in the general population. The species of dermatophyte implicated include Trichophyton, Microsporun and Epidermophyton with Trichophyton rubrum being responsible for most infections.

Medical Science, 2016, 20(80), 142-147

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CASE STUDY

Food Dependent Exercise Induced Anaphylaxis: A Case Report from Saudi Arabia

Malibary H

Food dependent exercise induced anaphylaxis is a rare, potentially fatal yet under-recognized condition in which patients develop anaphylaxis only if they exercise within a few hours of food ingestion. We present a case of food dependent exercise induced anaphylaxis in a 23 years old Saudi girl. She had three episodes of anaphylaxis, all happened during exercise that was preceded by food ingestion.

Medical Science, 2016, 20(80), 148-151

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Facial sensory disturbance associated with cervical compressive myelopathy

Naoki Kasahata

Cervical myelopathies do not usually cause facial sensory disturbance. We encountered, however, 2 patients developed facial sensory disturbance associated with cervical compressive myelopathy. We compared neurological findings and MRI findings of these patients.

Medical Science, 2016, 20(80), 152-157

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Solitary Metachronus Contralateral Adrenal Metastasis from Renal Cell Carcinoma

Suraci A, Suraci N

We present a case of solitary contralateralmetachronus adrenal metasisis five years after radical nephrectomy. The patient underwent laparoscopicadrenalectomy for primary renal cell carcinoma of the kidney for renal cell carcinoma. The patient was then treated with steroid replacement.

Medical Science, 2016, 20(80), 158-160

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