We are presenting an 11 years old girl with Atypical HUS (haemolytic uraemic syndrome). The patient presented to us as a case of acute gastritis with h/o haematuria since 3 days. On investigations, the child was found to have anaemia-Hb-6.5g% WBCcounts-8600/mm3 , platelets- 2.24lac/mm3 . Urea 93 mg/dl, Creatinine 2.7mg/dl, K+ 2.7mEq/L, Na+ 125mEq/L Peripheral smear showed moderate microcytic anaemia with Microspherocytes, Helmet cells, Schistocytes, Anisocytosis, suggestive of haemolytic anaemia. Child was found to have sky rising reticulocyte count of 28%, hence, she was suspected to be a case of atypical HUS. Factor H antibody levels were sent, which came out to be positive (5021 AU/ml), confirming the diagnosis of atypical HUS.
Myelo-protective activity of fractions of leaves extracts of Vitex doniana was investigated. Wistar rats (n=60) were intra-peritoneally induced for myelo-suppression with 3mg/kg bodyweight (b.wt) cyclophosphamide for 7 days.
We are presenting an 11 years old girl with Atypical HUS (haemolytic uraemic syndrome). The patient presented to us as a case of acute gastritis with h/o haematuria since 3 days.
